小儿轮状病毒肠炎患者的全血锌水平变化
2012-10-12张素娟高庆双
张素娟 高庆双
[摘要] 目的 探讨轮状病毒肠炎患儿发病急性期全血锌水平与正常儿童的区别,充分认识缺锌对儿童的危害和合理补锌的必要性。 方法 使用原子吸收分光光度法测定轮状病毒性腹泻患儿4 362例和健康儿童4 560例血锌含量。 结果 轮状病毒肠炎患儿血锌明显低于同龄健康儿童血锌水平,差异有统计学意义(P<0.05)。 结论 小儿患轮状病毒肠炎时血清锌的水平降低,大多数轮状病毒患儿处于缺锌状态。
[关键词] 儿童;轮状病毒肠炎;锌
[中图分类号] R725.1???[文献标识码] B???[文章编号] 2095-0616(2012)15-188-02
Change in the whole blood Zn level of children with rotavirus enteritis
ZHANG?Sujuan??GAO?Qingshuang
Department of Laboratory,Maternal and Child Care Service of Tangshan City in Hebei Province,Tangshan 063000,China
[Abstract] Objective To explore the difference in the whole blood level of zinc between the children with Rotavirus enteritis in the acute phase and the health children,and to understand the harm of Zn deficiency for children and the necessity of the reasonable supplement of zinc. Methods 4 362 cases of children with RV enteritis and 4 560 cases of health children were selected. The contents of blood Zn were determine by atomic absorption spectrophotometric method. Results The contents of blood Zn in children with RV enteritis were obviously lower than health children,the difference was significant (P<0.05). Conclusion The contents of blood Zn in children with RV enteritis reduced. The majority of children with RV enteritis were state of Zn deficiency.
[Key words] Children;Rotavirusenteritis;Zn
锌是人体生长发育所必需的微量元素之一,缺锌引起机体免疫力下降增加各种细菌病毒感染机会。轮状病毒性肠炎是婴幼儿的常见病。在不同的年龄段,轮状病毒(Rotavirus,RV)感染与锌缺乏两者之间存在着高度相关性。现将2009年7月~2010年12月来笔者所在医院就诊的的轮状病毒腹泻患儿和来健康体检的正常儿童全血锌测定结果进行比较,现报道如下。
1?资料与方法
1.1?一般资料
2009年7月~2010年12月来笔者所在医院就诊的腹泻患儿4 362例,其中男2 319例,女2 043例,按年龄分为3组:婴儿期(0~1岁),共1 126例;幼儿期(2~3)岁,共2 443例;学龄前期(4~6)岁,共793例;同一时期来医院查体的正常儿童4560例,按年龄分组:婴儿期(0~1岁),共1 329例;幼儿期(2~3)岁,共2 621例;学龄前期(4~6)岁共610例。
1.2?方法
1.2.1?仪器?北京博辉创新光电技术有限公司产BH5100S/T光谱仪。
1.2.2?试剂?轮状病毒测试采用北京万泰药业有限公司产A
群轮状病毒诊断试盒(胶体金法),效期内使用。锌的检测采用北京博辉创新光电技术有限公司产BH5100S/T光谱仪,随机配套试剂。……
