100例泌尿生殖道念珠菌病患者的菌种及药敏分析
2012-10-12王继红
王继红

[摘要] 目的 探析泌尿生殖道念珠菌病患者的菌种及药敏。 方法 对笔者所在医院2009~2011年接诊的100例泌尿生殖道念珠菌病患者的临床分析。 结果 通过科玛嘉念珠菌显色培养基的检测方法发现临床的96株菌均为白色念珠菌菌株,依据本试验中受试的菌株均在孵育24 h后判读结果,这一点可以充分的证实,科玛嘉念珠菌显色培养基以及微生物自动鉴定系统YBC酵母菌在白色念珠菌鉴定方面的实践应用价值和效果。 结论 在临床应用时应首选酮康唑、5-氟胞嘧啶和氟康唑几种药物,而其他药物因易出现不同程度的耐药趋势,故应谨用。
[关键词] 生殖道;念珠菌病;抗真菌;药敏试验;菌群分布
[中图分类号] R695???[文献标识码] B???[文章编号] 2095-0616(2012)15-116-02
Analysis of culture and drug sensitivity of 100 patients with genitourinary candidiasis
WANG?Jihong
Department of Dermatology, the Veteran Cadre's Rehabilitation Hospital of Henan,Zhengzhou 450003, China
[Abstract] Objective To analyze culture and drug sensitivity of the patients with genitourinary candidiasis. Methods 100 patients with genitourinary candidiasis collected in our hospital from 2009 to 2011 were analyzed. Results 96 strains of bacteria were all the candida albicans with the use of CHROMagar Candida. Though the results were judged after culture hatching for 24 hours,it may be confirmed richly that the using value and result of CHROMagar Candida and automatic identification system for microorganisms identificating candida albicans. Conclusion Ketoconazole, 5-fluorocytosine and fluconazole are the choice drug. other drugs should be used with caution because they occur easily different degrees of drug resistance.
[Key words] Genitourinary; Candidiasis; Antimycotic; Drug sensitive test; Bacterial distribution
生殖道念珠菌病主要分2种,一种是女性外阴念珠菌性病毒感染引发的炎症,一种是男性龟头念珠菌性炎症。目前,随着抗生素、各类激素,以及各种免疫性抑制药物在临床上的普遍应用,加之免疫缺陷性病毒(HIV)感染者的愈日剧增,同时伴随着抗真菌药物广泛应用于医疗实践,对这类病菌的组成结构造成了很大影响。当前,很多医院采用芽管试验和厚壁孢子试验的方法来鉴别白色念珠菌与非白色念珠菌的区别,然后利用科玛嘉念株显色培养基和微生物自动鉴定系统YBC酵母菌鉴定卡进一步分离菌株的菌种。
1?资料与方法
1.1?一般资料
选择笔者所在医院2009~2011年接诊的泌尿生殖道念珠菌病患者100例,年龄20~72岁,平均(35.0±4.2)岁;女52例,均出现以下症状:分泌物多呈豆渣状和乳液样,其中42例出现不同程度外阴瘙痒、阴部灼热以主白带增多症状;……
