黎希年

[摘要] 目的 分析安理申合并复方丹参滴丸治疗血管性痴呆的临床疗效。 方法?选择2005年1月～2011年12月在笔者所在医院进行血管性痴呆治疗的患者120例，随机分为治疗组、安理申组和对照组，每组各40例。对照组采用常规的治疗方式；安理申组在常规治疗基础上加予安理申治疗；治疗组再加复方丹参滴丸治疗，3组治疗前后进行MMSE、ADL积分比较分析。 结果 治疗组的疗效优于安理申组，安理申组优于对照组，差异有统计学意义（P＜0.05）。 结论 安理申对轻-中度认知功能损害治疗有效，能改善脑血管性痴呆患者的认知功能以及日常生活活动能力，合并复方丹参滴丸更能提高疗效，对提高患者的生存质量具有重要意义。

[关键词] 安理申；复方丹参滴丸；血管性痴呆

[中图分类号] R749.1+6???[文献标识码] A???[文章编号] 2095-0616（2012）15-50-02

Clinical research on 120 cases about vascular dementia

LI?Xinian

Department?of Neurological,Traditional?Chinese?and?Western?Medicine?Hospital of Yangjiang City,Yangjiang 529500,China

[Abstract] Objective To analyze the clinical effects on curing vascular dementia of aricept merging the compound Danshen dripping pills. Methods 120 patients which were selected from January 2005 to December 2011 in the author's hospital who received treatment on vascular dementia. The patients were randomly divided into treatment group, aricept group and control group. Each group had 40 patients. And the conventional treatment was applied in control group. Aricept group had the conventional treatment and aricept treatment included. Compound Danshen dripping pills were added in the treatment group to do treatment. Three groups going on MMSE and ADL integration were contrasted and analyzed. Results The curative effect in treatment group was superior to the aricept group and control group.In each group showed that the difference had statistical significance(P＜0.05). Conclusion Aricept has a curative effect on the light and medium impairment of cognitive function, and it can ameliorate the cognitive function of cerebral vascular dementia patients and the physical abilities in daily life. The approach of merging compound Danshen dripping pills could better improve the curative effect, which had a great significance for the quality of life of patients.

[Key words] Aricept;Compound Danshen dripping pills;Vascular dementia

血管性痴呆（vascular dementia，VD）属血管病所致精神障碍临床类型中的一种类型，也是脑血管疾病的临床转归的一种类型。随着人口老龄化及脑血管病的逐渐增多，VD发病率增多，近年来这类疾病有明显的上升趋势，但治疗手段不多。本研究通过常规治疗、加用安理申及安理申加用复方丹参滴丸治疗进行了临床对比观察，提出了医学用药治疗建议。

1?资料与方法

1.1?一般资料

选择2005年1月～2011年12月在笔者所在医院进行血管性痴呆治疗的患者120例随机分3组。治疗组：男22例，女18例，年龄56～90岁，平均（71.00±1.45）岁，病程2～7年，平均（4.56±1.75）年，多发性梗死20例，关键部位梗死所致痴呆7例，皮质下血管性痴呆10例，出血性痴呆3例。安理申……