瑶药土党参药材质量标准研究初探
2025-08-15潘柳伎刘凡吴佩莹欧春丽沈瑷瑷莫单丹王硕龚小妹
【中图分类号】R284.1 【文献标志码】A 【文章编号】1007-8517(2025)12-0045-04
DOI: 10.3969/j .issn.1007-8517.2025.12. zgmzmjyyzz202512011
Abstract:ObjectiveTo furtherimprove thequalitystandardof CampanumoeajavanicaBl.subsp.JavanicaBl.and providebasicdata,apreliminarystudyontheidentificationndcontentdeterminationofCampanumoeajauaicaBl.subsp.JavanicaBl.Herbs. MethodsTheextract,totalash,acid-insolubleash,andmoisturecontentofCampanumoeajavanicaBl.subsp.JavanicaBl.were determinedaccording togeneralprciplesofCnesePharmacopoeiaOOEdition.ResultsThemorphologicalcharacteristics,ross sectionandpowdermicroscopiccharacteristicsofCampanumoeajwanicaB.subsp.JavanicaBl.weredescribedindetailandused thethinlayerchomatographytoqualitativeidentificationofitsmthanolextract.ThetotalashcontentofCampanumoeajaanicaBl. subsp. Javanica Bl. was between 3.06% and 9.75% ,the acid-insoluble ash content was between 0.48% and 1.68% ,the 70% (204号 ethanol extractwasbetween 13.62% and 39.93% ,and the moisture content was between 9.75 % and 12.29 % .Conclusions The traitsofCampanumoeajavanicaBl.subsp.JavanicaBl.werestandardized.ThetotalashcontentofCampanumoeajavanicaBl.subsp.Javanica Bl. should not be more than 10.0% ,acid-insoluble ash content should not be more than 1.8% , 70% ethanol extract should not be lower than 13.0% ,and moisture content should not be more than 13% . The results provide a basis for the establishment of quality standards of Campanumoea javanica Bl. subsp. Javanica Bl.
KeyWords:Campanumoea Javanica Bl. subsp.Javanica Bl.;Characteristic Identification;Assaysin
土党参为桔梗科植物金钱豹(CampanumoeajavanicaBl.subsp.JavanicaBl.)的根,秋季采挖,洗净,晒干。土党参为瑶族常用药,瑶药名为梗挪台[],别名蜘蛛薯、马姑得、犬若来、桂党参、大花金钱豹[2]、奶参、土羊乳、白洋参、百丈光、川人参、浮萍参、南人参等[3-4]。常见于海拔1800m 之下 400m 之上的草坡和丛林里。主要在长江以南的省份分布,如浙江、江西、福建、台湾、湖南、广西、四川等地[4-5]。在广西主要分布在凤山、隆林、平果、隆安、大新桂平、藤县、贺县、阳朔、灌阳、全州、龙胜、靖西、那坡、宁明、田林各地[2.6]。其性平,味甘。有益气补脾、养肺镇咳、通乳的功效[4]。适应症为气血不足、气逆咳喘、吐泻、脾胃虚弱、乳少等症状。现代药理学研究[7-]表明,土党参中的提取物具有促胃肠道作用、免疫调节、改善脑损伤、抗疲劳等药理活性。为提高临床对瑶药土党参药材质量标准的把控,因而本文对瑶药土党参药材的形态特征,横切面、粉末显微特征进行了详细描述,同时其甲醇提取物进行了薄层定性鉴别,为建立瑶药土党参质量标准研究提供依据。
1仪器与试药
1.1仪器电子分析天平(厂家:德国Sartorius;型号:CP224S);生物显微镜(厂家:德国徕卡公司;型号:DM2000);箱式电阻炉(厂家:上海比尔得仪器实业有限公司;型号:SX2-4JOA);电热鼓风干燥箱(厂家:上海沪南科学仪器联营厂;型号:101-1);恒温浴锅(厂家:上海申生科技有限公司;型号:W201);高速万能粉碎机(厂家:天津泰斯特仪器有限公司);超声波清洗器(厂家:昆山超声波仪器有限公司;型号:KQ5200);超纯水机(厂家:美国Millipore;型号:Milli-QAcademic)。
1.2试剂 甲醇、乙醇、乙酸、乙酸乙酯,分析纯(厂家:成都市科龙化工试剂厂);……
