刘勇 蒋联建 梁功强 黄文文 尹东

【摘要】 肌肉减少症和骨关节炎（OA）同为年龄相关性疾病，患病率逐年增加。近年来国内外有一些研究报道中，OA与肌肉减少症关系密切，常呈伴发趋势，但两者相互关联的具体机制尚不明确。近年来国内外学者对两者的研究不断深入，肌肉减少症和OA两者的发病机制及两者之间的关系逐渐明了。本文通过总结近年来国内外关于肌肉减少症和OA的相关性研究，从定义、流行病学、发病机制、诊断和防治措施等方面进行综述，以期望为两种疾病的诊断及防治提供了一些参考和指导。

【关键词】 肌肉减少症 骨关节炎 运动 营养

Research Progress on Correlation between Sarcopenia and Osteoarthritis/LIU Yong， JIANG Lianjian， LIANG Gongqiang， HUANG Wenwen， YIN Dong. //Medical Innovation of China， 2024， 21（07）： -178

[Abstract] Both sarcopenia and osteoarthritis （OA） are age-related diseases， and the prevalence rate is increasing year by year. In recent years， there have been some research reports at home and abroad that OA and sarcopenia are closely related and often accompanied， but the specific mechanism of their correlation is still unclear. In recent years， scholars at home and abroad continue to deepen the study of both， and the pathogenesis of sarcopenia and OA and the relationship between them are gradually clear. This article summarizes the research on the correlation between sarcopenia and OA at home and abroad in recent years from the definition， epidemiology， pathogenesis， diagnosis and prevention measures， hoping to provide some reference and guidance for the diagnosis and prevention of the two diseases.

[Key words] Sarcopenia Osteoarthritis Exercise Nutrition

First-author's address： Graduate School of Youjiang Medical College for Nationalities， Baise 533000， China

doi：10.3969/j.issn.1674-4985.2024.07.039

隨着社会老龄化的加重，肌肉减少症和骨关节炎（OA）同为年龄相关性疾病，两种疾病的患病率逐年增加，公众对两种疾病的关注度也有所增加。近期有关脊柱疾病和髋部骨折与肌肉减少症联系的报道越来越多。这些报道表明，骨科患者显示出非常高的肌肉减少症患病率，且肌肉减少症会影响骨科疾病的预后。近年来国内外有一些研究报道，OA与肌肉减少症关系密切，但两者相互关联的具体机制尚不明确。近年来随着国内外学者对两者的研究不断深入，两种疾病的关系逐渐明了，故本文通过总结近年来国内外关于肌肉减少症和OA的相关性研究，从定义、流行病学、发病机制、诊断和防治措施等方面进行综述，以期望可以帮助学者了解肌肉减少症和OA两者之间的关系，为以后两者的预防和治疗提供一定的帮助和参考。……