戚挺 王维俊 马善朵 王欢 冯鑫

摘要 目的：探討益母草在早孕人工流产术后子宫修复以及激素水平变化中的作用。方法：选取2016年1月至2020年10月连云港市第一人民医院收治的早孕后人工流产手术患者106例作为研究对象，按照随机数字表法分为对照组和观察组，每组53例。全部患者接受常规人工流产手术。对照组术后给予屈螺酮炔雌醇片+八珍颗粒。观察组在对照组用药基础上给予益母草分散片。比较2组患者的各项症状缓解时间、性激素水平、阴道出血量评分、疼痛评分、不良反应发生率。结果：观察组的阴道流血时间、腹痛缓解时间、月经周期恢复时间、子宫内膜恢复时间均比对照组短（P<0.05）。治疗后，2组患者的雌二醇（E2）水平均增高，孕酮（P）和人绒毛膜促性腺激素（HCG）水平均降低。观察组治疗后的E2水平高于对照组，P、HCG水平均低于对照组，差异有统计学意义（P<0.05）。术后7 d，2组的阴道出血量评分、视觉模拟评分法（VAS）评分均降低。观察组阴道出血量评分、VAS评分均低于对照组（均P<0.05）。观察组的治疗效果优于对照组（P<0.05）。2组的不良反应发生率比较，差异无统计学意义（P>0.05）。结论：早孕接受人工流产手术的患者，在常规用药的基础上联合使用益母草，可有效抑制术后出血，加强子宫收缩，有助于改善术后性激素以及缓解疼痛，安全性良好。

关键词 益母草;早孕;人工流产;出血;屈螺酮炔雌醇片;子宫内膜;疼痛;性激素

Abstract Objective：To investigate the effects of Motherwort tablets in the repair of uterus and changes in hormone levels after artificial abortion in early pregnancy.Methods：A total of 106 female patients who underwent artificial abortion in their early pregnancy From January 2016 to October 2020，in the Department of Obstetrics and Gynecology of Lianyungang First People′s Hospital were included.According to the random number method，they were divided into a control group and an observation group，with 53 cases in each.All patients underwent oridianryabortion surgery.The control group was given drospirenone and ethinyl estradiol tablets and Bazhen granules after operation.The observation group was given extra motherwort dispersible tablets on the basis of the control group.The time of relieving symptoms，sex hormone levels，vaginal bleeding score，pain score，and incidence of adverse reactions were compared between the two groups.Results：The vaginal bleeding time，abdominal pain relief time，menstrual cycle recovery time，and endometrial recovery time in the observation group were shorter than those in the control group（P<0.05）.After treatment，the levels of estradiol（E2） in the two groups increased，and the levels of progesterone（P） and human chorionic gonadotropin（HCG） decreased.After treatment E2 of the observation group was higher than that of the control group，while P and HCG were lower than those of the control group（all P<0.05）.On the 7th day after operation，the vaginal bleeding scores and VAS scores of the two groups both decreased.The vaginal bleeding score and VAS score of the observation group were lower than those of the control group（both P<0.05）.The treatment effect of the observation group was better than that of the control group（P<0.05）.The difference in the incidence of adverse reactions between the two groups was not statistically significant（P>0.05）.Conclusion：For patients in early pregnancy undergoing artificial abortion，the combined of motherwort tablets and basic medication can inhibit postoperative bleeding，strengthen uterine contraction，help improving postoperative sex hormones and relieving pain with favorable safety.

Keywords Motherwort; Early pregnancy; Induced abortion; Hemorrhage; Drospirenone and desestrol tablets; Endometrium; Pain; Sex hormones

中图分类号：R282;R719.8;R717文献标识码：Adoi：10.3969/j.issn.1673-7202.2021.19.020

育龄期女性在避孕失败或者意外妊娠之后，经常采用……