张海妮

【摘要】目的：探究孟鲁司特钠治疗小儿咳嗽变异性哮喘的疗效。方法：将2020年2月-2021年1月在我院接受治疗的72例小儿咳嗽变异性哮喘患儿作为此次研究对象，并对上述患儿进行随机编号、重组，划至对照组（36例）和观察组（36例）中。在对上述两组患儿进行治疗时，对照组予以常规治疗，而观察组则在常规治疗基础上予以孟鲁司特钠治疗，最后对两组患儿经相应治疗后的各项指标进行对比分析。结果：经对比数据分析得出：观察组患儿经相应治疗后的临床疗效明显优于对照组，各对比数据间差异显著，即P<0.05，具有统计学意义。结论：对咳嗽变异性哮喘患儿进行治疗时，在常规治疗基础上加孟鲁司特钠治疗的效果更佳，建议在临床实践中广泛普及和应用。

【关键词】孟鲁司特钠;小儿咳嗽变异性哮喘;临床治疗效果

Objective： To explore the efficacy of montelukast sodium in the treatment of children with cough variant asthma. Methods： 72 children with cough variant asthma who were treated in our hospital from February 2020 to January 2021 were selected as the research objects， and the above children were randomly numbered and recombined， and divided into the control group （36 cases） and the observation group （36 cases）. In the treatment of the above two groups of children， the control group was given conventional treatment， while the observation group was given montelukast sodium on the basis of conventional treatment. Finally， the indicators of the two groups of children after corresponding treatment were compared and analyzed. Results： after comparative data analysis， the clinical efficacy indexes of the observation group were significantly better than those of the control group after corresponding treatment， and the differences between the comparative data were significant， that is， P < 0.05， with statistical significance. Conclusion： in the treatment of children with cough variant asthma， the effect of montelukast sodium on the basis of conventional treatment is better， which is recommended to be widely used in clinical practice.

[Key words] montelukast sodium; Cough variant asthma in children; Clinical effect

小兒咳嗽变异性哮喘是临床上一种较为特殊的哮喘病型，会对患儿身心健康产生不良影响，需要早确诊早治疗。目前，临床上主要采用糖皮质激素等药物进行治疗，但是会导致患儿在治疗期间出现不良反应，不宜长期采用这些药物进行治疗。经大量临床实践研究发现，孟鲁司特钠的加入可大大提升临床治疗安全性及有效性[1]。特此，本文针对孟鲁司特钠治疗小儿咳嗽变异性哮喘的疗效展开研究，并做出如下报告：

1资料与方法

1.1 一般资料

参与本次研究的72例患儿均为2020年2月-2021年1月我院收治的小儿咳嗽变异性哮喘患儿，且所有患儿家属均知晓本次研究内容，已于研究前签署意愿书。……