罗汇慧?姜志东?林青梅?徐莉

【摘要】目的 应用非沉浸式虚拟现实平台，探寻屈光参差和双眼不平衡情况的关系。方法  对体检人群中不同屈光状态的127名志愿者进行研究，检查其屈光状态和视功能（非沉浸式虚拟现实平台），记录和统计分析结果。结果 1 Hz频率的双眼整合刺激模式下，正常视力组与屈光参差组的双眼不平衡情况的差异均有统计学意义（P < 0.017），正常视力组中双眼不平衡（S1）的比例高于屈光参差组，单眼抑制（S2）的比例低于屈光参差组;而正常视力组和近视组、屈光参差组和近视组双眼不平衡情况差异均无统计学意义（P均> 0.017）。轻度屈光参差组和重度屈光参差组的双眼不平衡情况差异无统计学意义（P = 0.159）。结论 在非沉浸式虚拟现实平台的检查模式下发现屈光参差组和正常视力组双眼不平衡情况的构成有差异，屈光参差者中双眼严重不平衡的情况更多。

【关键词】双眼不平衡;屈光参差;双眼整合刺激模式

Assessment of binocular imbalance with a non-immersive virtual reality platform between emmetropes and anisometropes Luo Huihui， Jiang Zhidong， Lin Qingmei， Xu Li. Department of Cornea Ophthalmo-logy， Foshan Aier Eye Hospital， Foshan 528000， China Corresponding author， Xu Li， E-mail： xuli21315@ 163. com

【Abstract】Objective To explore the relationship between anisometropia and binocular imbalance by using a non-immersive virtual reality platform. Methods A total of 127 volunteers with different refractive status were recruited during physical examination. The refractive status and visual function （non-immersive virtual reality platform） were examined， and the results were recorded and statistically analyzed. Results Under the frequency of 1 Hz integrated binocular stimulation mode， the composition of binocular imbalance significantly differed among the normal vision and anisometropia groups （P < 0.017）. The ratio of binocular imbalance in the normal vision group （S1） was higher， and the ratio of monocular suppression （S2） was lower than that of anisometropia group. The composition of binocular imbalance did not significantly differ between the normal vision， anisometropia and myopia groups （both P > 0.017）. The composition of binocular imbalance did not significantly differ between the mild and severe anisometropia groups （P = 0.159）. Conclusions Using the non-immersive virtual reality platform， the composition of binocular imbalance significantly differs between the anisometropia and normal vision counterparts. The incidence of binocular imbalance is higher in anisometropia patients.

【Key words】Binocular imbalance;Anisometropia;Integrated binocular stimulation mode

屈光参差被认为是在等效球镜（Se）≥1.00 D的双眼屈光差。屈光参差引起的双眼视功能异常会对患者的生活和工作产生极大的影响[1-2]。双眼视知觉中的双眼不平衡状态为知觉在双眼呈现的不同刺激图像间竞争，表现为观察者看到2个图像交替出现[3]。本课题组前期通过回顾性调查发现不同程度的雙眼不平衡在正常视力者（双眼裸眼视力≥0.8且无眼疾）中占有很大比例，且可能会让双眼交替间歇使用[4]。但双眼不平衡情况与屈光参差的关系有待进一步探索。本研究收集体检人群中不同屈光状态的志愿者，使用频率为

1 Hz的双眼整合刺激模式对其双眼不平衡的情况进行测量，探寻屈光参差和双眼不平衡情况的关系，为临床探寻屈光参差的发生和进展机制提供新的思路。……