李玉军

摘  要：目的  探究在甲状腺功能亢进症（甲亢）患者诊断中应用酶免疫法测定游离三碘甲状腺原氨酸（FT3）水平的价值。方法  回顾性选取2017年12月～2019年12月期间东营市第五人民医院内分泌科接收确诊的甲亢患者100例作为研究病例，依照检测方法分为观察1组（免疫法检测）、观察2组（酶免疫法检测），各50例;并择取同期前来医院体检的健康人士50例作为对照组（酶免疫法检测）;对比三组纳入对象FT3水平以及病症诊断准确率。结果  观察1组、观察2组纳入对象FT3水平对比，无明显差异（P>0.05），但两组FT3水平均高于对照组（P<0.05）;观察2组纳入对象病症诊断准确率高于观察1组（P<0.05）。结论  在甲亢患者診断中，应用酶免疫法测定纳入对象FT3水平可有效提高诊断准确率，值得应用。

关键词：酶免疫法;FT3;甲亢;诊断;准确率

中图分类号：R446.1    文献标识码：A    文章编号：1009-8011（2021）-7-0007-03

Abstract： Objective  To investigate the value of measuring free triiodothyronine（FT3）levels by enzyme immunoassay in the diagnosis of patients with hyperthyroidism. Methods  One hundred patients with confirmed hyperthyroidism who were admitted to the Department of endocrinology of our hospital from December 2017 to December 2019 were retrospectively selected as study cases and divided according to the detection method into observation 1（immunoassay）， observation 2（enzyme immunoassay）， 50 patients each; and 50 healthy individuals who chose to come to our hospital during the same period were selected as control subjects （enzyme immunoassay）; FT3 levels of the three included subjects were compared to diagnostic accuracy of the condition.Results  The levels of FT3 of the included subjects in observation 1 and observation 2 groups were contrasted（P>0.05）， but the levels of FT3 in both groups were higher than those in the control group（P<0.05）， and the accuracy of the diagnosis of the included subjects in observation 2 group was higher than that in observation 1 group（P<0.05）.Conclusions  In the diagnosis of patients with hyperthyroidism， the levels of FT3 in included subjects using enzyme immunoassay can effectively improve the diagnostic accuracy rate， which deserves to be greatly promoted.

Keywords： enzyme immunoassay; FT3; hyperthyroidism; diagnosis; accuracy

甲亢全称为甲状腺功能亢进症，是指甲状腺腺体不适当的持续合成以及分泌过多的甲状腺激素而产生的人体内分泌系统疾病[1]。据临床调查显示，我国居民甲亢发生率为1.10%～1.60%，且近年来因遗传、感染病症发生率提升，药物滥用等因素影响，该病症发病率还呈现逐年上升趋势[2]。甲亢发生后，患者多见易激惹、失眠、怕热、多汗等明显症状，若未能及时诊治，还可能并发甲亢性心脏病、甲亢合并周期性麻痹等症状[3]，对身体健康以及日常生活造成严重的影响。因此，对甲亢患者进行有效诊治具有重要的意义。本文选取2017年12月～2019年12月医院内分泌科接收的甲亢患者100例作为研究病例，探究在甲亢患者诊断中应用酶免疫法测定游离三碘甲状腺原氨酸（FT3）水平的价值，为临床甲亢患者诊断提供参考。

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