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支气管肺泡灌洗治疗对老年重症肺炎患者临床效果及SaO2、PaO2、PaCO2水平的影响

2021-07-07侯思捷陈海生陈晓兴

中国现代医生 2021年11期

侯思捷  陈海生 陈晓兴

[摘要] 目的 探討支气管肺泡灌洗治疗对老年重症肺炎患者临床效果及SaO2、PaO2、PaCO2水平的影响。 方法 选取2018年9月至2020年9月于我院的老年重症肺炎患者114例,随机分为两组(对照组和研究组),各57例。对照组应用常规治疗,研究组在此基础上应用支气管肺泡灌洗治疗。观察对比两组治疗前、后的炎症因子变化情况和动脉血气情况及治疗效果。 结果 研究组治疗后WBC(7.8±2.6)×109/L、PCT(23.2±2.1)ng/mL、hs-CRP(4.5±2.1)mg/L低于对照组(10.2±3.1)×109/L、(31.3±6.2)ng/mL、(7.1±3.2)mg/L(P<0.05);研究组治疗效果(94.8%)高于对照组(82.4%)(P<0.05);研究组治疗后SaO2(89.6±5.2)%、PaO2(84.2±7.1) mmHg水平高于对照组(77.6±4.3)%、(77.1±5.2)mmHg,PaCO2水平(41.8±2.1) mmHg低于对照组(50.5±3.7)mmHg(P<0.05)。 结论 老年重症肺炎患者应用支气管肺泡灌洗治疗效果理想,可以降低机体的炎症因子指标,改善动脉血气情况,提高治疗效果。

[关键词] 支气管肺泡灌洗;老年重症肺炎;临床效果;SaO2;PaO2;PaCO2

[中图分类号] R563          [文献标识码] B          [文章编号] 1673-9701(2021)11-0084-04

The effect of bronchoalveolar lavage on the clinical effect and the level of SaO2, PaO2, and PaCO2 in elderly patients with severe pneumonia

HOU Sijie1   CHEN Haisheng2   CHEN Xiaoxing1

1.Department of Pharmacy, Foshan Hospital of Traditional Chinese Medicine, Foshan   528000, China; 2.Department of Laboratory Medicine, Foshan Hospital of Traditional Chinese Medicine, Foshan   528000, China

[Abstract] Objective To investigate the effect of bronchoalveolar lavage treatment on the clinical effect and the levels of SaO2, PaO2, and PaCO2 in elderly patients with severe pneumonia. Methods A total of 114 elderly patients with severe pneumonia in our hospital from September 2018 to September 2020 were selected and randomly divided into two groups (control group and study group), with 57 cases in each group. The control group was treated with conventional treatment, and the study group was treated with bronchoalveolar lavage on this basis. The changes of inflammatory factors and arterial blood gas before and after treatment, and the treatment effect in the two groups were compared. Results After treatment, WBC (7.8±2.6)×109/L, PCT (23.2±2.1) ng/mL, hs-CRP (4.5±2.1) mg/L in the study group were lower than those (10.2±3.1)×109/L, (31.3±6.2) ng/mL, (7.1±3.2) mg/L in the control group (P<0.05). The treatment effect of the study group (94.8%) was higher than that (82.4%) of the control group (P<0.05). The SaO2 (89.6±5.2)%, PaO2 (84.2±7.1) mmHg levels of the study group after treatment were higher than (77.6±4.3)%, (77.1±5.2) mmHg of the control group. The PaCO2 level (41.8±2.1) mmHg in the study group was lower than (50.5±3.7) mmHg in the control group (P<0.05). Conclusion The bronchoalveolar lavage in elderly patients with severe pneumonia has an ideal effect, which can reduce the body′s inflammatory factors, improve arterial blood gas, and improve the therapeutic effect.

[Key words] Bronchoalveolar lavage; Elderly severe pneumonia; Clinical effect; SaO2 level; PaO2 level; PaCO2 level

多种因素导致肺泡、肺间质炎症就是肺炎,如果患者发生急性呼吸道障碍、严重的低氧血症以及其他器官的功能障碍即可诊断为重症肺炎。目前临床中的诊断能力不断提高,且抗菌药物种类也越来越多,但给予患者全身性的抗菌治疗后,仍有治疗不佳的患者[1]。而老年重症肺炎患者相对比较特殊,病情进展快,较危重,易伴有其他功能障碍,导致死亡。近几年,医疗技术不断发展,肺部疾病的治疗和诊断中纤维支气管镜的价值较高,而支气管肺泡灌洗技术就是通过支气管镜将生理盐水注入到患者的肺泡中,同时立即吸出,给予靶向治疗,从而消除患者的缺氧状态,清除细菌,提高患者的换气、通气功能[2]。本文主要探讨老年重症肺炎患者应用支气管肺泡灌洗治疗的效果,现报道如下。

1资料与方法

1.1一般资料

选取2018年9月至2020年9月于我院的老年重症肺炎患者114例,随机分为对照组和研究组,每组各57例。……

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