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高血压病舌象客观化特征与痰证素的相关性研究

2021-04-29段梦遥张晓晴董易杭蒋欣琪胡志希彭清华

湖南中医药大学学报 2021年1期
关键词:高血压

段梦遥 张晓晴 董易杭 蒋欣琪 胡志希 彭清华

〔摘要〕 目的 觀察高血压病患者痰证素舌象特征,并进行病理程度与舌象特征的相关性分析。方法 选取湖南中医药大学第一附属医院2019年3月至2019年8月高血压病患者315例,依据痰证素积分分为3组,即非痰证组(99例)、痰证轻病组(116例)、痰证重病组(100例)。应用舌诊仪采集标准舌象,基于颜色空间及纹理指标,使用Pearson及Kruskal-Wallis H检验对患者舌象特征进行相关性分析。结果 随着痰证程度的加重,舌质(tongue body, TB)、舌苔(tongue coating, TC)颜色指标红色(red, R)值、绿色(green, G)值、蓝色(blue, B)值均升高,且R值、B值的变化幅度要大于G值;TB亮度(intensity, I)值升高、饱和度(saturation, S)值降低;纹理指标TB角度方向二阶矩降低,TB熵值、TB平均值升高;TC面积/全舌面积升高。痰证素的病理等级与TB-R、TB-G、TB-B、TC-R、TC-G、TC-B、TB-I、TB熵值、TB平均值、TC面积/全舌面积呈正相关(P<0.05),与TB-S、TB角度方向二阶矩呈负相关(P<0.05)。结论 舌象客观化指标对高血压病痰证反映灵敏,舌象特征与中医学理论及临床结论基本一致,舌象客观化指标对高血压病的诊断具有独特的优势和应用价值。

〔关键词〕 舌象;高血压;痰;证素;客观化

〔中图分类号〕R241.25        〔文献标志码〕B       〔文章编号〕doi:10.3969/j.issn.1674-070X.2021.01.003

〔Abstract〕 Objective To analyze the correlation between pathological degree and tongue features through observing tongue image of syndrome element of phlegm in hypertension patients. Methods A total of 315 hypertension patients in The First Affiliated Hospital of Hunan University of traditional Chinese medicine (TCM) from March 2019 to August 2019 were recruited, and divided into non-phlegm syndrome element group (n=99), mild phlegm syndrome element group (n=116) and severe phlegm syndrome element group (n=100) based on the phlegm syndrome element score. Standard tongue image of each patient was collected using a tongue diagnosis instrument. The correlation of tongue image characteristics of patients was analyzed based on the color spaceand texture indexes by using Pearson and Kruskal-Wallis H test. Results With the aggravation of the degree of phlegm syndrome element in hypertension patients, the color index values of red (R), green (G) and blue (B) of tongue body (TB) and tongue coating (TC) increased, and the increasing degree of R and B was much higher than that of G value; the value of TB intensity (I) increased and the saturation (S) decreased; the value of texture index of TB angular second moment decreased, while TB entropy and TB mean increased; TC area/total tongue area increased. The pathological grade of syndrome element of phlegm was positively correlated with TB-R, TB-G, TB-B, TC-G, TC-B, TB-I, TB entropy, TB mean and TC area/total tongue area (P<0.05), while negatively correlated with TB-S and TB angular second moment (P<0.05). Conclusion Objective index of the tongue image is sensitive in reflecting syndrome element of phlegm in hypertension. Tongue features are basically consistent with TCM theories and clinical conclusions. Therefore, objective index of the tongue image has unique advantages and application value in the diagnosis of hypertension.

〔Keywords〕 tongue features; hypertension; phlegm; syndrome element; objectify

流行病学调查显示,目前中国高血压病患病人数约2.9亿,其死亡率居各病之首,占居民疾病死亡构成的40%[1]。作为引发心脑血管病第一危险因素的高血压病,可对人体重要靶器官造成损伤,如何更好地预防与控制高血压病是当下研究的热点与难点。舌为心之外侯,可灵敏地反映人体生理病理变化,现代研究表明,舌象变化与高血压病密切相关[2-3]。当前舌象研究正朝着客观化、智能化的方向不断发展且日益成熟[4-5],诸多学者在“数字舌图采集”和“舌象特征处理”两个方面进行研究[6-12],为舌象的临床采集和分析提供了良好的技术支持。

本研究对高血压病进行证素辨证,以痰证素为切入点建立研究网络,使用新型舌诊仪器进行舌象采集,采用新版计算机专业舌象分析软件进行舌象分析,以期得到更精准、更先进、可以被广泛参考的研究结果。……

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