张雨琪 李宗友 王映辉 李敬华 于琦 朱玲 姜威 杨佳楠 宋源 于彤

摘要：目的  构建用方经验知识图谱，辅助北京皮肤科赵炳南、朱仁康流派学术思想与临床经验传承。方法  以书籍、论文为数据来源，制定包含疾病、证候、症状、病程阶段、治则、方剂、中药、用法、医家及其间关系的知识框架。基于框架编写知识抽取表，获取包含多类实体、关系的知识，将每条知识的唯一编码设置为所涉实体、关系的知识来源属性。参考术语标准，计算术语相似度，使用Protégé为证候术语构建本体。将本体对关系的匿名类表述修改为三元组，与知识图谱融合，选择图数据库Neo4j，导入知识并发布于在线平台。结果  构建了包含5 999个实体、20 312条关系的赵炳南、朱仁康皮肤科流派用方经验知识图谱。约束涉及医家间有师承关系，可获取流派知识;约束知识来源属性相同，可区分涉及多类实体的已有知识与因知识融合而显现的隐性知识;也可通过实体、关联深度的筛选进行快速检索。结论  通过知识图谱可便捷地获取、对比流派知识，能够辅助名老中医知识的传承、创新。

关键词：学术流派;知识图谱;方剂;中医皮肤科;隐性知识

中图分类号：G353.1;R27    文献标识码：A    文章编号：2095-5707（2021）02-0001-05

DOI： 10.3969/j.issn.2095-5707.2021.02.001        开放科学（资源服务）标识码（OSID）：

Construction of Knowledge Map on Experience in TCM Prescriptions of Dermatology Schools of Zhao Bingnan and Zhu Renkang

ZHANG Yu-qi， LI Zong-you， WANG Ying-hui， LI Jing-hua， YU Qi， ZHU Ling， JIANG Wei， YANG Jia-nan， SONG Yuan， YU Tong*

（Institute of Information on Traditional Chinese Medicine， China Academy of Chinese Medical Sciences， Beijing 100700， China）

Abstract： Objective To construct a knowledge map of TCM prescriptions to assist the inheritance of the academic thoughts and clinical experience of Beijing dermatology schools of Zhao Bingnan and Zhu Renkang. Methods Books and papers of the academic schools were selected as the data source. A knowledge schema including disease， syndrome， symptom， disease stage， treatment， prescription， usage， doctor and their relationships was constructed. A template based on the schema was developed to extract knowledge containing multiple types of entities and relationships. A unique code of each piece of knowledge was set as the attribute of the knowledge source of the entity and relationship involved. Referring to terminology standards， term similarity was calculate， and Protégé was uses to construct ontology for syndrome terms. The anonymous class expression of the ontology pair relationship was modified into triples， merged with the knowledge map. Map database

名老中醫学术思想和临床经验是中医药传承的重要内容，这离不开中医学术流派的研究[1]。学术思想的传承和创新会对流派内方剂配伍理论产生深远影响，体现出流派个性知识[2-3]。因此，中医药传承需要特别关注用方经验。……