吴素霞 康碧珠 王强

【摘要】 目的：探究CT多平面重建聯合仿真内镜图像对腺样体肥大合并阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患儿病情严重程度的评估价值，并分析病情严重程度与T淋巴细胞的相关性。方法：选取2018年1月-2020年1月于本院接受治疗的80例腺样体肥大并发OSAHS患儿作为试验组，另选取50例于本院接受体格检查的健康儿童作为对照组。两组均进行鼻内镜与CT多平面重建与仿真内镜图像检查。以鼻内镜检测结果为金标准，比较CT多平面重建联合仿真内镜图像与鼻内镜对试验组腺样体肥大程度、腺样体阻塞程度的评估结果。比较两组CT多平面重建联合仿真内镜图像检测参数及T淋巴细胞。分析腺样体肥大程度、腺样体阻塞程度与T淋巴细胞水平的相关性。结果：CT多平面重建联合仿真内镜图像与鼻内镜对试验组腺样体肥大及阻塞程度检测结果比较，差异均无统计学意义（P>0.05）。试验组鼻咽部截面积与口咽部截面积均低于对照组（P<0.05）。试验组CD4+、CD8+以及CD4+/CD8+均高于对照组（P<0.05）。腺样体肥大程度、阻塞程度与CD4+、CD8+、CD4+/CD8+均呈正相关（P<0.05）。结论：CT多平面重建联合仿真内镜图像对于腺样体肥大合并OSAHS患儿的病情具有较为客观、准确、全面的诊断，能够为患儿的治疗以及病情评估提供一定的临床参考，且患儿病情与T淋巴细胞具有一定的相关性。

【关键词】 CT多平面重建 仿真内镜图像 腺样体肥大 OSAHS T淋巴细胞

Application Value of CT Multi-plane Reconstruction and Simulated Endoscopic Image in Children with Adenoid Hypertrophy Complicated with OSAHS and Correlation between Severity of Disease and T Lymphocytes in Children/WU Suxia， KANG Bizhu， WANG Qiang. //Medical Innovation of China， 2021， 18（24）： 067-071

[Abstract] Objective： To explore the value of CT multiplane reconstruction and simulated endoscopic image in evaluating the severity of adenoid hypertrophy complicated with obstructive sleep apnea hypopnea syndrome （OSAHS） in children， and to analyze the correlation between the severity of disease and T lymphocytes in children. Method： A total of 80 children with adenoid hypertrophy complicated with OSAHS treated in our hospital from January 2018 to January 2020 were selected as the experimental group， and another 50 healthy children who received physical examination in our hospital were selected as the control group. Nasal endoscopy， CT multiplane reconstruction and simulated endoscopic image were performed in both groups. With the results of nasal endoscopy as the gold standard， the evaluation results of CT multiplane reconstruction and simulated endoscopic image and nasal endoscopy on the degree of adenoid hypertrophy and adenoid obstruction in the experimental group were compared. CT multiplane reconstruction and simulated endoscopic images detection parameters and T lymphocytes were compared between two groups. The correlation of adenoid hypertrophy， adenoid obstruction and T lymphocyte level was analyzed. Result： There were no statistical significance in the results of adenoid hypertrophy and obstruction degree detected by CT multiplane reconstruction and simulated endoscopic image and nasal endoscopy （P>0.05）. The cross-sectional area of nasopharynx and oropharynx in the experimental groups were lower than those in the control group （P<0.05）. CD4+， CD8+ and CD4+/CD8+ in the experimental group were higher than those in the control group （P<0.05）. The degree of adenoid hypertrophy and obstruction were positively correlated with CD4+， CD8+ and CD4+/CD8+ （P<0.05）. Conclusion： CT multiplane reconstruction and simulated endoscopic image can provide a relatively objective， accurate and comprehensive diagnosis for the condition of children with adenoid hypertrophy combined with OSAHS， which can provide certain clinical reference for the treatment and condition evaluation of children， and the condition of children has a certain correlation with T lymphocytes.

[Key words] CT multi-plane reconstruction Simulated endoscopic image Adenoid hypertrophy OSAHS

T lymphocytes

First-author’s address： Quanzhou Women’s and Children’s Hospital， Quanzhou 362000， China

doi：10.3969/j.issn.1674-4985.2021.24.017

腺样体又被称为咽扁桃体或增殖体，是位于鼻咽部顶部与咽后壁处的淋巴组织，表面呈现橘瓣样，腺样体会随着个体年龄的增长而逐渐长大，4～6岁为增殖的旺盛时段，以后逐渐退化，至10岁时开始萎缩，至成年则大部分消失[1]。……