余欢 谭晨光 翟东子 葛书君 涂秋月 李金香

[摘要] 目的 運用数据挖掘技术，分析探讨近五年针灸治疗帕金森病的选穴配伍规律，为临床治疗和进一步研究提供参考。 方法 以“帕金森病OR震颤麻痹OR颤证AND针OR针刺OR针灸”为主题词，时间范围为2014年10月31日至2019年10月31日，对中国知网、万方、维普和PubMed 数据库中针灸治疗帕金森病的相关临床研究文献进行检索，最终筛选出符合纳入标准的文献36篇。将纳入文献中与治疗选穴相关的资料录入Excel数据库进行整理、归纳、统计，并使用SPSS Modeler 18.0统计学软件中的Apriori关联规则方法对所选穴位进行关联分析。结果 临床治疗中应用频次最高的腧穴为风池穴;应用穴数最多的经脉为督脉，应用频次最高的经脉为足少阳胆经;分部选穴中多选头颈部腧穴;特定穴中多选交会穴与原穴;选穴配伍以“合谷-太冲”“风池-合谷”“风池-太冲”“曲池-太溪”相配最常用。 结论 现代临床上针灸治疗帕金森病多根据病位病性选用祛风要穴、督脉穴及头颈部腧穴，且重视交会穴与原穴的应用以多脏多经同调;腧穴配伍以治肝为主，重在熄风止颤，兼以补肾填精益髓。

[关键词] 数据挖掘;针灸疗法;帕金森病;选穴配伍规律;文献研究

[中图分类号] R742.5          [文献标识码] B          [文章编号] 1673-9701（2021）03-0149-07

Investigation on the regularity of acupoint selection and compatibility of moxibustion in treating Parkinson′s disease in recent five years based on data mining

YU Huan1   TAN Chen′guang1   ZHAI Dongzi1   GE Shujun1   TU Qiuyue1   LI Jinxiang2

1.Hunan University of Chinese Medicine， Changsha   410208， China; 2.Department of Acupuncture and Massage Rehabilitation， the First Hospital of Hu′nan University of Chinese Medicine， Changsha   410007， China

[Abstract] Objective To analyze and discuss the regularity of acupoint selection and compatibility of moxibustion in treating Parkinson′s disease in recent five years by applying the data mining skill， so as to provide reference for clinical treatment and further research. Methods With the subject words of "Parkinson′s disease OR paralysis agitans OR tremor syndrome AND needle OR acupuncture OR moxibustion”， from October 31st， 2014 to October 31st， 2019， the relevant clinical research literatures on acupuncture and moxibustion for Parkinson′s disease in China national knowledge infrastructure （CNKI）， Wanfang， VIP and PubMed databases were searched， and finally 36 literatures meeting the inclusion criteria were screened out. The data related to acupoint selection in the literature were entered into excel database for collation， induction and statistics， and Apriori association rule method in SPSS Modeler 18.0 software was used to carry out association analysis on the selected acupoints. Results Fengchi（GB20） acupoint was the most frequently used acupoint in clinical treatment. The meridian with the largest number of acupoints was governor vessel（GV）， and foot lesser yang gallbladder meridian（GB） was the most frequently used meridian. Head and neck acupoints were more frequently selected from different parts. Crossing acupoints and source acupoints were more frequently selected from specific acupoints. It was most frequently used in pairs to select acupoints with "Hegu（LI4）-Taichong（LR3）"， "Fengchi（GB20）-Hegu（LI4）"， "Fengchi（GB20）-Taichong（LR3）" and "Quchi（LI11）-Taixi（KI3）". Conclusion In modern clinic， key acupoints with the function of dispelling wind， GV acupoints and head and neck acupoints are more frequently selected in the acupuncture and moxibustion treatment of Parkinson′s disease according to the diseases′ site and pathology. Meanwhile， the applications of crossing acupoints and source acupoints are attached more importance to make more viscera and more meridians coordinated. The compatibility of acupoints is mainly to treat liver， focusing on dispelling wind and stopping tremor，and tonifying kidney combined with replenishing essence and marrow.

[Key words] Data mining; Acupuncture therapy; Parkinson′s disease; The regularity of acupoint selection and compatibility; Literature research

帕金森病（Parkinson's disease，PD）又称震颤麻痹，是一种常见的中枢神经系统变性疾病，表现为静止性震颤、肌强直、运动迟缓及姿势步态异常等[1]。本病多发于中老年人[2]，随着年龄增长患病率逐渐增高[3]。我国PD患者已超过260万，位居世界首位，每年发病率约为797/10万[4]。……