胡丹丹

【摘 要】目的：分析预防性抗感染治疗对胎膜早破的临床价值及可行性。方法：盲选50例患者均分两组，普通组无需治疗，研究组应用预防性抗感染治疗，对比结果。结果：研究组产妇的感染率更低，差异显示有意义（P<0.05）；而且观察两组的母婴结局能够发现，研究组的母婴结局也好于普通组，差异显示也有意义（P<0.05）。结论：在胎膜早破的产妇中应用预防性抗感染治疗是可行的，而且还能有效保障母婴双方的安全。

【关键词】预防性抗感染；PROM；感染；可行性

Clinical value and feasibility of prophylactic anti infective therapy for premature rupture of membranes

Hu Dandan

Hami Central Hospital Affiliated to Xinjiang Medical University Xinjiang Hami 839000，China

【Abstract】Objective：To analyze the clinical value and feasibility of preventive anti infection therapy for premature rupture of membranes. Method：The 50 patients were randomly divided into two groups. The general group did not need treatment， and the study group applied preventive anti infection treatment. The results were compared.Results：The infection rate of pregnant women in the study group was lower， and the difference was significant（P<0.05）； Moreover， by observing the maternal and infant outcomes of the two groups， it can be found that the maternal and infant outcomes of the study group are better than those of the general group， and the difference is also significant （P<0.05）. Conclusion：It is feasible to apply preventive anti infection treatment in pregnant women with premature rupture of membranes， and it can effectively ensure the safety of both mothers and infants.

【Key？Words】Prophylactic anti infection；PROM；Infected；Feasibility

胎膜早破（Premature rupture of membranes，PROM）是指在臨近分娩前产妇的胎膜发生自然破裂，这也是围生期产妇最容易发生的一种并发症，一旦发生就会严重影响到母婴双方安全[1]。导致PROM发生的因素并不少，例如产妇的胎位异常或者是临产前产妇营养状态不稳等都有可能致使产妇发生PROM，但最主要的因素还是生殖道发生感染。胎膜早破很大程度上会对产妇的宫内感染以及母婴结局产生不良影响，但是具体的致病因素还尚未明确。一旦产妇发生PROM，产妇及新生儿都会因此受到不良影响，所以临床必须及时处理该情况[2]。基于此，本次对PROM产妇展开了治疗与未治疗的对比观察，共选用了50例产妇作为本次的观察对象，现报告如下。

1.1 一般资料

盲选我院于2020年2月至2021年1月接收的PROM患者，总共50例并均分两组。产妇均经过病理学确诊，产妇能感应到阴道流出大量的液体，经过检查后发现阴道后穹隆存在羊水积聚的现象或者是羊水从宫口有发生流出，严格排除条件并不符合者，例如有明显全身感染者或者是有酗酒或者是吸毒史的产妇等。……