周江 张敏 吴研 尚香玉

[摘要] 目的 探討冠状动脉介入治疗（PCI）冠心病的短期死亡风险危险因素。 方法 选取我院2020年1—9月收治的冠心病患者130例，所有患者均经PCI术治疗。根据患者术后6个月内的死亡情况，将其分成生存组、死亡组。比较两组临床特征，包括性别、年龄、体质量指数、冠脉病变部位、家族史、高血压、高尿酸血症、糖尿病、吸烟史、心源性休克、冠心病类型，分析冠心病患者PCI术后短期死亡与临床特征的关系。经Logistic回归模型分析PCI术后短期死亡的危险因素。 结果 在130例患者中，有24例（18.46%）在术后6个月死亡，有106例（81.54%）术后6个月生存。死亡组年龄≥60岁、高血压、高尿酸血症、心源性休克占比分别为62.50%、58.33%、50.00%、66.67%，高于生存组的33.96%、21.70%、17.92%、11.32%，差异有统计学意义（P<0.05）。Logistic回归分析显示年龄≥60岁、高血压、高尿酸血症、心源性休克是PCI术后短期死亡的危险因素（P<0.05）。结论 冠心病患者PCI术后短期死亡主要与年龄、高血压、高尿酸血症、心源性休克存在关联，临床需对此引起重视。

[关键词] 冠心病;冠状动脉介入术;心源性休克;高血压;高尿酸血症

[中图分类号] R541.4          [文献标识码] B          [文章编号] 1673-9701（2021）33-0050-04

[Abstract] Objective To investigate the short-term mortality risk and risk factors of coronary heart disease （CHD） after percutaneous coronary intervention （PCI）. Methods A total of 130 patients with coronary heart disease admitted to our hospital from January to September 2020 were selected. All patients were treated with PCI. The patients were divided into the survival group and the death group according to the death of patients within 6 months after the operation. The clinical characteristics were compared between the two groups， including gender， age， body mass index， location of coronary artery disease， family history， hypertension， hyperuricemia， diabetes， smoking history， cardiogenic shock， and type of coronary heart disease. The relationship between short-term death after PCI and clinical characteristics in patients with coronary heart disease was analyzed. The logistic regression model was used to analyze the risk factors for short-term death after PCI. Results Of the 130 patients， 24 （18.46%） died six months after surgery， and 106 （81.54%） survived six months after surgery. The age≥60 years， hypertension， hyperuricemia， and cardiogenic shock in the death group accounted for 62.50%， 58.33%， 50.00%， and 66.67%， respectively， which were higher than 33.96%， 21.70%， 17.92%， and 11.32% in the survival group， and the differences were statistically significant （P<0.05）. Logistic regression analysis suggested that age≥60 years， hypertension， hyperuricemia， and cardiogenic shock were risk factors for short-term death after PCI （P<0.05）. Conclusion The short-term death of patients with coronary heart disease after PCI is mainly related to age， hypertension， hyperuricemia， and cardiogenic shock. Clinical attention should be paid to this.

[Key words] Coronary heart disease; Coronary intervention; Cardiogenic shock; Hypertension; Hyperuricemia

目前，冠心病在我国的患病率、死亡率均有逐年增高的趋势，其对患者生活质量影响较大[1-2]。冠状动脉介入术（Percutaneous coronary intervention，PCI）已证实对冠心病治疗有效，现已成为治疗该病的常用手段。大部分患者在治疗后，病情显著缓解，取得较理想的效果[3]。然而，仍有部分患者术后因各种因素导致死亡[4]。为了降低PCI术后死亡风险，临床必须明确与之相关的危险因素，以便尽快采取预防措施，减少死亡发生，改善预后。本研究旨在分析PCI治疗冠心病的短期死亡风险及危险因素，现报道如下。

1 资料与方法

1.1 一般资料

选取我院2020年1—9月收治的冠心病患者130例，所有患者均经PCI术治疗，对患者临床资料进行回顾性分析。……