新生儿重症监护室多重耐药菌种类及药敏结果分析
2020-10-21伊怀文
伊怀文



【摘 要】 目的:分析新生儿重症监护室含有的多种耐药菌类别,并进行药敏实验,探究治疗方法。方法:研究对象选择我院重症监护室内感染多重耐药菌的新生儿80例,分析其感染多重耐药菌的种类及分析情况。结果:此次80例患儿感染多重耐药菌主要分为革兰阴性菌、革兰阳性菌两类,前者主要包括:肺炎克雷伯菌、鲍曼不动杆菌、大肠埃希菌、产期肠杆菌等,后者主要包括:表皮葡萄球菌、金黄色葡萄球菌等。分布主要区域为痰液、尿液、血液等处,尤其痰液占比最高(p<0.05)。多重耐药菌对常用抗生素四环素、万古霉素、阿米卡星、环丙沙星等敏感性较高,对青霉素、头孢菌素等药物耐药性较强。结论:新生儿重症监护室内包含多种多重耐药菌,应根据药敏结果合理选用治疗药物,以保证疗效。
【关键词】新生儿;重症监护室;多重耐药菌种类;药敏结果
【中图分类号】R722.1 【文献标识码】B 【文章编号】1002-8714(2020)05-0012-02
【Abstract】 Objective:To analyze the types of multidrug-resistant bacteria contained in neonatal intensive care unit, and to conduct drug sensitivity experiments to explore treatment methods. Methods The study subjects selected 80 neonates with multi-drug resistant bacteria in intensive care unit in our hospital, and analyzed the types and analysis of multi-drug resistant bacteria. Results The multi-drug resistant bacteria in 80 children were divided into two types: Gram-negative bacteria and Gram-positive bacteria. The former mainly included: Klebsiella pneumoniae, Acinetobacter baumannii, Escherichia coli, and maternity. Enterobacteria, etc., the latter mainly include: Staphylococcus epidermidis, Staphylococcus aureus and the like. The main areas of distribution were sputum, urine, blood, etc., especially the proportion of sputum was the highest (p<0.05). And are more resistant to penicillin and cephalosporin. Conclusion The neonatal intensive care unit contains a variety of multi-drug resistant bacteria. The therapeutic drugs should be selected according to the results of drug susceptibility to ensure the efficacy.
【Key words】 neonatal; intensive care unit; multi-drug resistant species; drug susceptibility results
重症监护室收治的新生儿多为早产儿或存在严重疾病的患儿,免疫功能较弱,需要长时间留院观察、治疗,期间接受多项操作,极容易感染多重耐药菌。最近几年,伴随第三代头孢菌素类抗生素的大量使用,耐药菌越来越多,对临床治疗造成了困难[1]。合理使用抗生素药物治疗新生儿始终是医疗界需要研究的内容。本文以2018.4-2019.4我院收治80例感染多重耐药菌的重症新生儿为例,分析其菌株种类,并以常用抗生素为例进行药敏实验分析耐药性,具体如下。
1 资料与方法
1.1 一般资料
本次研究时间选定2018年4月-2019年4月,研究对象选择我院重症监护室内感染多重耐药菌的新生儿80例,包括男童42例,女童38例,胎龄短则27周,长则32周,平均(30.4±0.2)周,体重最轻1000g,最重2500g,平均体重(1534.8±11.0)g。
1.2 方法
采集患儿身上细菌进行培养制备,利用细菌鉴定仪,严格遵照相关标准操作完成药敏检验。……
