消化性溃疡治疗中奥美拉唑联合甲硝唑及阿莫西林的临床效果观察
2020-10-21段治松
段治松

【摘 要】目的:探讨采取奥美拉唑+甲硝唑+阿莫西林的三联疗法治疗消化性溃疡的效果。方法:选取100例患者为研究对象,分成观察组40例,该组采取奥美拉唑+甲硝唑+阿莫西林治疗,对照组40例,该组采取呋喃唑酮+雷尼替丁+甲硝唑治疗,对比两组治疗效果。结果:经1个月的治疗,观察组总有效率94.00%高于对照组80.00%,差异有统计学意义(P<0.05)。结论:采取奥美拉唑+甲硝唑+阿莫西林的联合用药方法治疗消化性溃疡的疗效显著,值得推广。
【关键词】消化性溃疡;奥美拉唑;甲硝唑;阿莫西林;疗效
【中图分类号】R573【文献标识码】B 【文章编号】1002-8714(2020)07-0286-01
[Abstract] Objective: To explore the effect of the triple therapy of omeprazole + metronidazole + amoxicillin on peptic ulcer. Methods: 100 patients were selected as the research object and divided into observation group of 40 cases. This group was treated with omeprazole + metronidazole + amoxicillin. The control group was 40 cases. Azole treatment, compared the treatment effect between the two groups. Results: After 1 month of treatment, the total effective rate in the observation group was 94.00% higher than that in the control group 80.00%, and the difference was statistically significant (P<0.05). Conclusion: The combination of omeprazole + metronidazole + amoxicillin is effective in the treatment of peptic ulcer and is worthy of promotion.
[Keywords] peptic ulcer; omeprazole; metronidazole; amoxicillin; efficacy
消化性潰疡属于一种消化系统疾病,疾病多是因胃酸分泌紊乱或感染幽门螺杆菌(Hp)所致,该疾病的发生会对正常生活及工作造成巨大的影响,所以需要采取有效的方法进行治疗[1]。在消化性溃疡治疗上,常用三联疗法治疗,三联疗法的方案多种多样,但各种方案的疗效存在差异[2]。本次研究中就探讨了采取奥美拉唑+甲硝唑+阿莫西林的三联疗法治疗的效果,报告如下。
1 资料与方法
1.1 一般资料
选取2018年2月-2019年4月收治的100例消化性溃疡患者为研究对象,所有患者均经内镜检查、Hp感染检测及胃液分析等检查确诊,患者均无用药禁忌签署知情同意书。按照随机数字表法分成以下两组:实验组50例,男29例,女21例;年龄21~65岁,平均(43.2±1.3)岁。对照组50例,男28例,女22例;年龄20~64岁,平均(42.9±1.2)岁。一般资料上对比无显著差异(P>
0.05)。
1.2 方法
对照组采取呋喃唑酮+雷尼替丁+甲硝唑的三联疗法治疗,具体如下:口服呋喃唑酮片(山西云鹏制药有限公司,国药准字号H14023937,规格0.1g*100s),100mg/次,3次/d;口服盐酸雷尼替丁片……
