孟凡全

[摘要] 目的 分析評估经输尿管镜钬激光术治疗尿道狭窄伴尿道结石的临床效果。方法 该次研究方便选取的96例尿道狭窄伴尿道结石患者，于2018年2月—2019年1月收治该院，按随机数字表法分成两组，其中对照组48例采取常规电切镜冷刀术治疗，观察组48例则采取经输尿管镜钬激光术治疗，进一步对两组临床治疗效果进行比较。结果 ①观察组治疗总有效率为93.75%，与对照组的75.00%对比显著更高，两组数据差异有统计学意义（χ2=10.136，P<0.05）。②在手术时间、碎石时间、住院时间方面，观察组分别为（30.21±1.26）min、（20.17±0.65）min、（7.20±1.00）d，均明显短于对照组的（46.88±3.45）min、（45.90±0.72）min、（13.80±1.20）d;观察组术中出血量为（10.98±2.10）mL，与对照组的（24.56±2.14）mL对比明显更少;两组数据差异有统计学意义（t=10.263、11.259、5.682、10.278，P<0.05）。③在术后并发症总发生率方面，观察组为4.17%，与对照组的20.83%对比显著更低，两组数据差异有统计学意义（χ2=10.278，P<0.05）。结论 针对尿道狭窄伴尿道结石患者，采取经输尿管钬激光术治疗效果限制，可缩短手术时间、碎石时间、住院时间，减少术中出血量，降低术后并发症发生率。

[关键词] 经输尿管镜钬激光术;尿道狭窄;尿道结石;临床效果

[中图分类号] R4          [文献标识码] A          [文章编号] 1674-0742（2020）06（a）-0046-03

The Effect of Transureteroscopic Holmium Laser in the Treatment of Urethral Stricture with Urethral Stones

MENG Fan-quan

Department of Urology， Linyi Traditional Chinese Medicine Hospital， Linyi， Shandong Province， 276000 China

[Abstract] Objective To analyze and evaluate the clinical effect of ureteroscopic holmium laser in the treatment of urethral stricture with urethral stones. Methods Conveniently selection of 96 patients with urethral stricture and urethral calculi included in this study were admitted to the hospital from February 2018 to January 2019， and were divided into two groups according to the random number table method. Among them， 48 patients in the control group were treated with conventional resection microscopy surgical treatment， 48 cases in the observation group were treated with ureteroscopy holmium laser， and the clinical treatment effects of the two groups were further compared. Results 1.The total effective rate of treatment in the observation group was 93.75%， which was significantly higher than the 75.00% in the control group. There was a statistically significant difference between the two groups of data （χ2=10.136， P<0.05）. 2.In terms of operation time， lithotripsy time， and hospitalization time， the observation group was （30.21±1.26） min， （20.17±0.65） min， and （7.20±1.00） d， which were significantly shorter than those of the control group （46.88±3.45） min， （45.90±0.72） min， （13.80±1.20） d; the intraoperative blood loss in the observation group was （10.98±2.10） mL， which was significantly less compared with （24.56±2.14） mL in the control group; the data in the two groups There were significant statistical differences （t= 10.263， 11.259， 5.682，10.278，P<0.05）. 3.In terms of the total incidence of postoperative complications， the observation group was 4.17%， which was significantly lower than the 20.83% of the control group. There was a statistically significant difference between the two groups of data （χ2=10.278， P<0.05）. Conclusion For patients with urethral stricture and urethral calculi， the use of transureteral holmium laser treatment is limited， which can shorten the operation time， lithotripsy time， hospitalization time， reduce intraoperative blood loss， and reduce the incidence of postoperative complications

[Key words] Transureteral holmium laser; Urethral stricture; Urethral stones; Clinical effect

尿道狭窄，为泌尿系统常见的一种疾病，该类患者的主要表现为：排尿困难、尿潴留、尿失禁等;而尿道结石则为泌尿外科常见的疾病之一，患者常有排尿困难症状，主要受到尿道狭窄、感染、潴留性囊肿等因素所致。当患者出现尿道狭窄伴尿道结石，则会对患者的生活质量造成较大程度的影响。因此，临床建议，针对尿道狭窄伴尿道结石患者，在明确诊断的基础上，进一步采取有效的治疗方法，以期改善患者的病情及生活质量。同时，近年来，临床研究发现经输尿管镜钬激光术在治疗尿道狭窄伴尿道结石患者治疗中的效果显著，且术后并发症少，安全高效，值得借鉴及应用。鉴于此，该课题将该院2018年2月—2019年1月收治的96例尿道狭窄伴尿道结石患者作为研究的对象，其目的是分析评价经输尿管镜钬激光术治疗的效果，现报道如下。

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