龙丽芸

[摘要]目的 探讨CO2点阵激光联合透明质酸导入对增生性瘢痕的效果。方法 选取2018年1月～2019年7月于我院门诊就诊并收入院行手术治疗的30例增生性瘢痕患者作为研究对象，依照双盲法将其分为观察组（15例）及对照组（15例）。观察组患者使用透明质酸导入联合CO2点阵激光治疗，对照组患者仅给予CO2点阵激光治疗。比较分析两组患者的临床效果及不良反应发生情况。研究两组患者治疗前后的色泽、柔软度、厚度及血管分布评分。结果 两组患者的不良反应总发生率、治疗总有效率比较，差异无统计学意义（P>0.05）。治疗前，两组的色泽、柔软度、厚度及血管分布评分比较，差异无统计学意义（P>0.05）;治疗后，观察组的色泽、柔软度、厚度及血管分布评分低于对照组，差异有统计学意义（P<0.05）。结论 使用CO2点阵激光联合透明质酸导入治疗增生性瘢痕，可增强创面改善效果，利于预后良好发展。

[关键词]增生性瘢痕;CO2点阵激光;透明质酸;颜色饱和度

[中图分类号] R644          [文献标识码] A          [文章编号] 1674-4721（2020）7（a）-0035-04

Clinical effect of CO2 dot lattice laser combined with hyaluronic acid in the treatment of hypertrophic scars

LONG Li-yun

Department of Burns and Plastic Surgery， Ganzhou People′s Hospital， Jiangxi Province， Ganzhou   341000， China

[Abstract] Objective To investigate the effect of CO2 dot lattice laser combined with hyaluronic acid introduction on hypertrophic scars. Methods From January 2018 to July 2019， 30 patients with hypertrophic scars who were treated in the outpatient clinic and then admitted into the hospital for surgery were selected as the research subjects. They were divided into observation group （n=15） and control group （n=15） by double blind method. In the observation group， hyaluronic acid combined with CO2 lattice laser was used， while in the control group， CO2 lattice laser alone was used. The clinical effect and adverse reactions of the two groups were compared. The changes of the scores of color， softness， thickness or blood vessel distribution in the two groups were explored. Results The total incidence of adverse reactions and the total effective rate of treatment were compared between the two groups， and the differences were not statistically significant （P>0.05）. Before treatment， there were no statistically significant differences in the scores of color， softness， thickness or blood vessel distribution between the two groups （P>0.05）. After treatment， the scores of color， softness， thickness and blood vessel distribution of the observation group were lower than those of the control group， with statistical significance （P<0.05）. Conclusion The use of CO2 dot lattice laser combined with hyaluronic acid in the treatment of hypertrophic scars can enhance the effect of wound and facilitate good prognosis.

[Key words] Hypertrophic scars; CO2 dot lattice laser; Hyaluronic acid; Color saturation

增生性瘢痕是外科较常见病症，是指创伤后留下瘢痕，在组织修复、愈合过程中发生过度增生形成的病变[1]。增生性瘢痕病因可分为局部因素和全身因素，其中，局部因素主要包括炎症、异物进入、皮肤张力等;全身因素主要指遗传、内分泌及年龄等。按照病情严重程度，可将增生性瘢痕分为轻度、重度及高度增生3类[2-3]。增生性瘢痕表面形状不规则，质地实韧且潮红充血，患者普遍具有瘙痒及灼痛症状，在高温或辛辣食物刺激下可加剧，其次增生性瘢痕还会对患者的外在形象造成影响，产生自卑感，严重时还会引起患者的心理健康问题，对患者的个人形象、皮肤健康及心理均有较大影响[4]。目前，C……