唐宗纯 袁敏 李永亮

摘要  目的：探析腦梗死恢复期患者采取丹红注射液联合氢氯吡格雷口服进行治疗对改善神经功能的效果。方法：选取2017年5月至2019年11月马鞍山十七冶医院收治的脑梗死恢复期患者66例作为研究对象，按照随机数字表法随机分为对照组与观察组，每组33例。对照组采取氢氯吡格雷口服治疗，观察组采取丹红注射液联合氢氯吡格雷口服治疗，比较2组患者治疗有效率、神经功能缺损评分（NIHSS）、日常生活能力评分（ADL）、运动功能、不良反应发生率、洼田饮水试验等指标。结果：与对照组比较，观察组治疗有效率明显较高，差异有统计学意义（ P <0.05）;与对照组比较，观察组的NIHSS评分较低，ADL评分较高，差异有统计学意义（ P <0.05）;观察组的不良反应发生率明显低于对照组，差异有统计学意义（ P <0.05）;2组Ⅱ级、Ⅲ级比较，差异有统计学意义（ P <0.05）;2组用药后洼田饮水试验分级比较，差异有统计学意义（ P <0.05）。结论：脑梗死恢复期患者采取丹红注射液联合氢氯吡格雷口服进行治疗能够提升治疗效果、改善神经功能，安全性高，可加快患者康复速度。

关键词  脑梗死恢复期;丹红注射液;氢氯吡格雷;神经功能;口服用药;运动功能;日常生活能力;治疗效果

Observation on Recovery Period of Cerebral Infarction by Danhong Injection Combined with Hydrochloride

TANG Zongchun， YUAN Min， LI Yongliang

（Ma′anshan Seventeenth Metallurgical Hospital， Ma′anshan 243000， China）

Abstract Objective： To explore the effects of Danhong Injection combined with hydrochloride orally on the treatment of patients with cerebral infarction at the recovery stage to improve neurological function.  Methods： A total of 66 patients with cerebral infarction recovery who were treated in Ma′anshan Seventeenth Metallurgical Hospital from May 2017 to November 2019 were selected as the research objects and were divided into a control group and an observation group according to the random number table， with 33 cases in each group. The control group was treated with oral hydrochloride， and the observation group was treated with Danhong Injection combined with oral hydrochloride. Indexes such as the total treatment efficiency， neurological deficit score（NIHSS）， daily life ability score（ADL）， motor function， incidence of adverse reactions， and drinking water test in Watian were compared.  Results： Compared with the control group， the total effective rate of treatment in the observation group was significantly higher（ P <0.05）; compared with the control group， the NIHSS score in the observation group was lower and the ADL score was higher（ P <0.05）; the incidence of adverse reactions in the observation group was significantly lower than that in the control group（ P <0.05）; the comparison of grade Ⅱ and grade Ⅲ between the 2 groups was statistically significant（ P <0.05）; there was a significant difference in the grading comparison of the drinking water test Watian between the 2 groups（ P <0.05）.  Conclusion： Danhong Injection combined with hydrochloride orally for treatment of patients with cerebral infarction recovery can improve the therapeutic effect， improve nerve function， have high safety， and can speed up the recovery of patients.

Keywords  Recovery period of cerebral infarction; Danhong Injection; Hydroclopidogrel; Nerve function; Oral medication; Motor function; Ability of daily life; Therapeutic effects

中图分类号：R289.5;R743 文献标识码：A  doi： 10.3969/j.issn.1673-7202.2020.14.022

脑血管常见疾病中脑梗死具有较高的发病率，又可命名为缺血性脑卒中疾病，主要是因为脑部血液供应异常，或者由于脑部缺血、脑部缺氧等引起部分脑组织出现坏死而造成的疾病[1]。动脉硬化作为脑梗死疾病的常见致病因素，临床症状以头晕、头痛、恶心、呕吐等为主，部分患者甚至会出现昏迷、失语等症状，对患者的家庭生活以及身体健康会产生严重的影响，在脑血管疾病治疗中受到了极大的关注[2]。氢氯吡格雷作为脑梗死疾病中常见的西医治疗药物，其在改善神经功能方面有一定的优势，但效果不明显。因此，应该及时寻求一种有效的辅助治疗措施用于临床，促使患者的治疗预后明显改善。……