拜糖平与二甲双胍治疗2型糖尿病的临床效果研究
2020-05-21俞国和曹霞
俞国和 曹霞


[摘要] 目的 探讨拜糖平与二甲双胍药物在治疗2型糖尿病患者中的应用效果。方法 2017年3月—2019年5月,选取该院78例2型糖尿病患者作为研究对象,按照随机数字表法分为对照组39例(采用二甲双胍治疗),观察组39例(采用拜糖平治疗),比较两组患者的临床效果、不良反應以及血糖水平。结果 对比患者临床治疗有效率差异有统计学意义(P<0.05)。对照组患者空腹血糖水平、餐后2 h血糖水平,均明显高于观察组(P<0.05)。对照组患者不良反应发生率为28.21%,明显高于观察组5.13%(P<0.05)。结论 通过对比拜糖平与二甲双胍药物在治疗2型糖尿病患者中的应用效果,结果证实,与二甲双胍药物相比,拜糖平药物能够减少不良反应的发生,改善其血糖水平,提高临床治疗效果,临床应用价值及临床推广极高。
[关键词] 拜糖平;二甲双胍;2型糖尿病;血糖水平
[中图分类号] R587.2 [文献标识码] A [文章编号] 1672-4062(2020)02(a)-0048-03
The Clinical Effect of Acarbose and Metformin in the Treatment of Type 2 Diabetes
YU Guo-he, CAO Xia
The First Hospital of Longyan City, Longyan, Fujian Province, 364000 China
[Abstract] Objective To explore the application effect of Acarbose and metformin in the treatment of patients with type 2 diabetes. Methods From March 2017 to May 2019, 78 patients with type 2 diabetes in the hospital were selected as the research subjects. According to the random number table method, 39 patients in the control group (treated with metformin) and 39 patients in the observation group (treated with Acarbose), to compare the clinical effects, adverse reactions and blood glucose levels of the two groups of patients. Results There was a statistically significant difference in clinical treatment effectiveness between patients(P<0.05). The fasting blood glucose level and 2 h postprandial blood glucose level in the control group were significantly higher than those in the observation group(P<0.05). The incidence of adverse reactions in the control group was 28.21%, which was significantly higher than the observation group 5.13%(P<0.05). Conclusion By comparing the application effect of Baitangping and metformin in the treatment of patients with type 2 diabetes, the results confirm that compared with metformin, Acarbose can reduce the incidence of adverse reactions, improve its blood glucose level, and improve the clinical treatment effect, improve clinical application value and clinical promotion.
[Key words] Acarbose; Metformin; Type 2 diabetes; Blood glucose level
2型糖尿病在临床上属于一种较为常见的机体糖代谢障碍性疾病,加之伴随着人们生活水平的提高以及饮食习惯的不注意,以至于导致2型糖尿病的发生率不断增加,并呈现年轻化趋势,且多表现为多饮、多食、多尿、体重下降症状[1-2]。一旦患有2型糖尿病,就需长期接受治疗,然而随着病程的延长,将会引发一系列的并发症,严重影响了患者身心健康。研究表明[3],临床上采用拜糖平与二甲双胍药物在治疗2型糖尿病时,均能够起到显著的临床效果。为探讨拜糖平与二甲双胍药物的治疗效果,该文以该院于2017年3月—2019年5月收治的2型糖尿病患者78例为研究对象,现报道如下。
1 资料与方法
1.1 一般资料
选取该院78例2型糖尿病患者作为研究对象,按照随机数字表法分为对照组39例,观察组39例。对照组男患者27例,女患者12例;年龄43~76岁,平均(59.5±4.5)岁。观察组男患者25例,女患者14例;年龄45~76岁,平均(60.5±4.9)岁。一般资料差异无统计学意义(P>0.05)。具有可比性。
纳入标准:①参与该次研究活动的人员均自愿参与,并签署知情同意书;②患者没有心、肝、肺等脏器疾病;③患者未患有痴呆、认知障碍、精神疾病等;④符合美国糖尿病学会发布的《2016年糖尿病医学诊疗标准》中的相关标准。……p>
