[摘要] 目的 觀察分析胰岛素不同给药方法治疗糖尿病的临床效果。方法 随机择取2018年4月—2019年4月于该院收治的122例糖尿病患者作为研究对象，按照入院时间将122例患者分为对照组（n=61例）与观察组（n=61例），分别给予不同的胰岛素治疗方法。对照组行胰岛素常规注射治疗，观察组行胰岛素泵持续注射，比较两组糖尿病的临床有效率、血糖水平、血糖达标时间、胰岛素应用剂量、低血糖发生率。结果 观察组61例糖尿病的临床有效率96.7%大于对照组的有效率67.2%，差异有统计学意义（χ2=7.998，P<0.05）。观察组的低血糖率3.4%小于对照组的14.8%，差异有统计学意义（P<0.05）。观察组治疗后的空腹血糖水平、餐后2 h血糖水平、糖化血红蛋白水平、血糖达标时间、胰岛素应用剂量均小于对照组，差异有统计学意义（P<0.05）。结论 应用胰岛素泵持续给药，可有效治疗糖尿病，可更好的控制糖尿病的血糖水平，可减少低血糖率，临床应用安全性更高。

[关键词] 糖尿病;不同给药方法;常规注射;胰岛素泵持续注射;血糖水平;胰岛素应用剂量

[中图分类号] R587.1          [文献标识码] A          [文章编号] 1672-4062（2020）02（a）-0013-03

Observation of Clinical Effect of Different Insulin Administration Methods on Diabetes

XU Hua

Houcun Central Health Center， Donggang District， Rizhao， Shandong Province， 276800 China

[Abstract] Objective To observe and analyze the clinical effects of different insulin administration methods on diabetes. Methods A total of 122 diabetic patients admitted to the hospital from April 2018 to April 2019 were randomly selected as study subjects. According to the time of admission， 122 patients were divided into control group（n=61 cases） and observation group （n=61 patients） were given different insulin treatment methods. The control group received conventional insulin injection treatment， and the observation group received continuous insulin pump injection. The clinical efficacy， blood glucose level， blood glucose reaching time， insulin dosage， and incidence of hypoglycemia were compared between the two groups. Results The clinical effective rate of 61 cases of diabetes in the observation group was 96.7% greater than the effective rate of 67.2% in the control group， and the difference was statistically significant（χ2=7.998，P<0.05）. The hypoglycemia rate in the observation group was 3.4% less than the control group's 14.8%， and the difference was statistically significant（P<0.05）. The fasting blood glucose level， 2h postprandial blood glucose level， glycated hemoglobin level， blood glucose compliance time， and insulin application dose in the observation group were less than those in the control group， and the difference was statistically significant（P<0.05）. Conclusion Continuous application of insulin pump can effectively treat diabetes， better control the blood sugar level of diabetes， reduce the rate of hypoglycemia， and have higher clinical safety.

[Key words] Diabetes; Different administration methods; Conventional injection; Continuous injection of insulin pump; Blood glucose level; Insulin application dose

随着我国社会飞速发展，人们的饮食结构与生活方式均有显著改变，人们的糖分摄入量越来越高，糖尿病发病率也有明显升高。糖尿病属于内分泌科常见病，患者的主要特征为赤血高血糖。临床认为，糖尿病的发生与遗传因素、环境因素、饮食因素、生活习惯等多种因素相关[1]。以往，临床往往给予胰岛素口服治疗糖尿病，但口服胰岛素虽有一定效果，但对于病情比较严重的患者而言，效果并不理想。因此，临床提议皮下注射胰岛素治疗糖尿病。既往研究认为[2]，皮下注射胰岛素治疗糖尿病的效果优于口服胰岛素。但近年来，临床推出了一种新型治疗方法—胰岛素泵持续注射治疗。随机择取2018年4月—2019年4月于该院收治的122例糖尿病患者作为研究对象，对比分析了胰岛素常规皮下注射与胰岛素泵持续注射的治疗效果，报道如下。……