探讨急性脊髓炎的临床特征以及激素治疗的效果
2019-10-21孙茂苍
孙茂苍
【摘 要】目的:探讨急性脊髓炎的临床特征以及激素治疗的效果。方法:选取我院2017年12月-2018年12月收治的62例急性脊髓炎患者随机分为观察组和对照组,每组31例,对照组采用地塞米松为核心药物进行治疗,观察组采用甲基强的松龙为核心药物进行治疗。对比两组治疗有效率和不良反应发生率。结果:患者临床表现较多,也带有一定的特异性,但个体间存在差异。观察组治疗有效率高于对照组,不良发应发生率低于对照组,差异具有统计学意义(p<0.05)。结论:急性脊髓炎的临床特征为起病急,发病时有低热、神经根痛、肢体麻木、运动障碍、组织功能障碍特点。采用甲基强的松龙可有效改善患者病情,且安全性理想。
【关键词】急性脊髓炎;地塞米松;临床特征;甲基强的松龙
Abstract:Objective To investigate the clinical features of acute myelitis and the effect of hormone therapy.Methods: 62 cases of acute myelitis in our hospital from Dec 2017 to Dec 2018 were randomly divided into observation group (n = 31) and control group (n = 31).The control group was treated with dexamethasone as the core drug.The observation group was treated with methylprednisolone as the core drug.The effective rate of treatment and the incidence of adverse reactions were compared between the two groups.Results: there were many clinical manifestations and specificity, but there were differences among individuals.The effective rate of treatment in the observation group was higher than that in the control group.The difference was statistically significant (p < 0.05).Conclusion: acute myelitis is characterized by acute onset, low fever, nerve root pain, numbness of limbs, dyskinesia and tissue dysfunction.Methylprednisolone can effectively improve the patient's condition, and the safety is ideal.
Key words: T
【中图分类号】R725.51【文献标识码】A【文章编号】1005-0019(2019)17-0-01
前言:急性脊髓炎(acute myelitis)是一种发病较急的炎症,一般受到感染因素影响发病,该疾病可导致运动障碍、排泄失禁以及感觉障碍等。因急性脊髓炎与其他疾病存在症状上的相似性,设法了解患者临床特征十分必要[1]。同时,目前应对炎症的药物较多,应在现有基础上分析价值最理想的治疗方案,我院研究如下:
1 资料与方法
1.1 一般资料 于我院2017年12月-2018年12月收治的急性脊髓炎患者中,选取62例随机分为观察组和对照组,每组31例。对照组31例患者,男17例,女14例,年龄24-65岁,平均(45.2±2.8)岁。观察组31例患者,男16例,女15例,年龄26-64岁,平均(45.4±2.7)歲。两组一般资料差异无统计学意义(p>0.05)。
1.2 方法 对照组采用地塞米松(国药准字H20113234;广西万德药业股份有限公司生产)为核心药物进行治疗。取地塞米松20mg,融入240mL葡萄糖注射液(5%浓度)中,于患者外周静脉建立通道,进行滴注治疗。每d给药一次,持续治疗10d,患者病情好转可增加地塞米松用量50%,继续治疗10d,之后改为每d用药25mg至停药[2]。……p>
