邹明洋　曾玉蓉　曾丽思　吴美妮

【摘要】 目的：探讨软组织韧带样型纤维瘤病的CT影像学特征与生物学特征。方法：回顾性分析42例软组织韧带样型纤维瘤病患者的CT影像学资料与临床资料，分析软组织韧带样型纤维瘤病的CT影像学特征与生物学特征。结果：病灶平扫密度主要呈低密度，病灶边界主要呈部分不清或完全不清，病灶形态主要呈分叶状或不规则状，病灶未见钙化，增强扫描均表现为不均匀强化，随着不同时相逐步强化，跨解剖间室生长、累及神经血管束、累及骨质均较为多见;病灶均无包膜，病灶主要由梭形细胞和胶原纤维束构成，病灶有侵袭性生长倾向，病灶内无囊性变、坏死区;原发性与复发性软组织韧带样型纤维瘤病的边缘、形态、累及神经血管束、累及骨质、病灶平扫密度的构成比比较，差异均无统计学意义（P>0.05）;原发性软组织韧带样型纤维瘤病的跨解剖间室生长的构成比显著低于复发性软组织韧带样型纤维瘤病，差异有统计学意义（P<0.05）。结论：软组织韧带样型纤维瘤病具有一定的生物学特征，能反映在CT像学表现上。

【关键词】 软组织韧带样型纤维瘤病; CT影像学特征; 软组织肿瘤

CT Imaging and Biological Characteristics of Desmoid-type Fibromatosis/ZOU Mingyang，ZENG Yurong，ZENG Lisi，et al.//Medical Innovation of China，2019，16（18）：-106

【Abstract】 Objective：To discuss the CT imaging and biological characteristics of desmoid-type fibromatosis.Method：CT imaging and clinical data of 42 patients with desmoid-type fibromatosis were analyzed retrospectively.CT imaging and biological characteristics of desmoid-type fibromatosis were analyzed.Result：The density of lesions on plain scan was mainly low density，the margin of the lesion was partly or completely unclear，the lesions were lobulated or irregular in shape，no calcification was found in the lesion，enhanced scanning showed heterogeneous enhancement，with the gradual strengthening of different phases，growth shadow across anatomical compartment，involving neurovascular bundle shadow，involving bone shadow are more common，the lesions were not enveloped by capsule，the lesions were mainly composed of spindle cells and collagen fiber bundle，the lesions had aggressive growth tendency，there was no cystic degeneration and necrosis in the lesion.There was no significant difference between primary and recurrent desmoid-type fibromatosiss margin，morphology，involvement of neurovascular bundle，involvement of bone and density of lesion on plain scan（P>0.05）.The proportion of cross-anatomical ventricular growth shadow in primary desmoid-type fibromatosis was significantly lower than that in recurrent desmoid-type fibromatosis（P<0.05）.Conclusion：Desmoid-type fibromatosis has certain biological characteristics and can be reflected in CT imaging.

【Key words】 Desmoid-type fibromatosis; CT imaging features; Soft connective tissue tumor

First-authors address：Huizhou Municipal Central Hospital，Huizhou 516001，China

doi：10.3969/j.issn.1674-4985.2019.18.027

軟组织韧带样型纤维瘤病是指起源于肌肉内结缔组织及其被覆的筋膜或腱膜的单克隆纤维母细胞肿瘤，亦称韧带样瘤、硬纤维瘤或侵袭性纤维瘤病，生物学行为介于良恶性肿瘤之间，具有侵袭性生长、局部复发倾向的特点[1-3]。术前诊断、定位有利于软组织韧带样型纤维瘤病的外科治疗，目前软组织韧带样型纤维瘤病难以与其他类型的软组织肿瘤相鉴别[4-7]。为此……