毕宪坤

摘要：目的  探讨加味苦参汤熏洗对肛周脓肿术后创面愈合的临床效果。方法  选取2018年1月～2019年1月我院收治的行一次性根治术治疗的肛周脓肿术后患者60例，随机分为对照组和观察组，各30例。对照组术后采用高锰酸钾溶液熏洗，观察组采用加味苦参汤熏洗，比较两组临床效果、住院与创面愈合时间以及炎症因子水平。结果  观察组治疗总有效率为93.33%，明显高于对照组的73.33%，差异有统计学意义（P<0.05）。观察组住院时间、创面愈合时间短于对照组[（12.34±2.10）d vs（19.30±2.71）d]、[（20.34±1.51）d vs（28.24±1.93）d]，差异有统计学意义（P<0.05）。治疗后，观察组IL-6、CRP水平低于对照组[（60.35±11.22）ng/L vs（80.18±12.27）ng/L]、[（4.25±0.48）mg/L vs（6.43±1.16）mg/L]，差异有统计学意义（P<0.05）。结论  加味苦参汤熏洗治疗肛周脓肿术后患者疗效显著，利于促进创面愈合，减轻机体炎性因子水平。

关键词：肛周脓肿;创面愈合;加味苦参汤;炎性因子

中图分类号：R574.8                                文献标识码：A                                  DOI：10.3969/j.issn.1006-1959.2019.16.052

文章编号：1006-1959（2019）16-0155-02

Abstract：Objective  To investigate the clinical effect of Jiawei Kushen decoction on wound healing after perianal abscess surgery.Methods  60 patients with perianal abscess treated by one-time radical surgery admitted to our hospital from January 2018 to January 2019 were randomly divided into control group and observation group， 30 cases each. The control group was treated with potassium permanganate solution and the observation group was treated with Jiawei Kushen decoction. The clinical effects， hospitalization and wound healing time and inflammatory factor levels were compared between the two groups.Results  The total effective rate of the observation group was 93.33%， which was significantly higher than that of the control group 73.33%，the difference was statistically significant （P<0.05）. The length of hospital stay and wound healing time in the observation group were shorter than those in the control group [（12.34±2.10） d vs （19.30±2.71） d]， [（20.34±1.51） d vs （28.24±1.93） d]， the difference was statistically significant （P<0.05）. After treatment， the levels of IL-6 and CRP in the observation group were lower than those in the control group [（60.35±11.22） ng/L vs （80.18±12.27） ng/L]， [（4.25±0.48） mg/L vs （6.43±1.16） mg/L]，the difference was statistically significant （P<0.05）.Conclusion  The effect of Jiawei Kushen decoction on the treatment of perianal abscess is significant， which is beneficial to promote wound healing and reduce the level of inflammatory factors.

Key words：Perianal abscess;Wound healing;Jiawei Kushen soup;Inflammatory factor

肛周膿肿（perianal abscess）属于常见病、多发病，其指的是肛管与直肠周围间隙或组织发生的急性化脓性感染，并逐渐发展为肛管、直肠周围脓肿，多因肛腺或肛窦等炎症所致[1]，临床多表现为疼痛，且多数伴有发热，若治疗不及时，易引发败血症，严重影响患者的日常生活和工作。目前临床主要采取手术治疗，一次性根治术最为常见，而手术质量的一个重要评价指标即创面愈合质量，但由于患者手术部位较为特殊，且分泌物和创面较大等因素均易造成患者创面愈合不佳。本文主要探讨加味苦参汤熏洗对肛周脓肿术后创面愈合的临床效果，现报道如下。

1资料与方法

1.1一般资料  选取2018年1月～2019年1月佳木斯市中医院收治的行一次性根治术治疗的肛周脓肿术后患者60例，按随机数字表法分为对照组和观察组，各30例。对照组中男18例，女12例;年龄21～65岁，平均年龄（42.83±11.32）岁;病程2～18 d，平均病程（7.97±2.54）d;脓肿部位：高位16例，低位14例。……