冯居秦 张道维 帖晓瑛

摘 要：目的 观察活血美颗粒联合中药面膜治疗面部雀斑的疗效。方法 选取2016年9月～2018年8月经中西医确诊的光老化雀斑99例，按数字随机法分为两组。治疗组53例使用活血美颗粒联合自制中药面膜进行治疗；对照组46例使用千白氢醌乳膏治疗。1月为1疗程，连续治疗3疗程，观察治疗后面部恢复情况，并对其治疗效果进行判断。结果 治疗组总有效率和雀斑治疗前后评分下降指数分别为75.47%、（0.62±0.11）；而对照组总有效率和雀斑治疗前后评分下降指数分别为56.52%、（0.45±0.24），差异有统计学意义（P<0.05）。结论 活血美颗粒联合中药面膜治疗面部雀斑，疗效满意。

关键词： 活血美；中药面膜；雀斑

中图分类号：R758.4+3 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.20.037

文章编号：1006-1959（2018）20-0125-03

Abstract：Objective To observe the therapeutic effect of Huoxuemei Granules combined with traditional Chinese medicine mask on facial freckles.Methods A total of 99 cases of photoaging freckles diagnosed by Chinese and Western medicine from September 2016 to August 2018 were selected and divided into two groups according to the numerical random method.In the treatment group，53 cases were treated with Huoxuemei Granules combined with homemade Chinese medicine mask；In the control group，46 cases were treated with Hydroquinone Cream，1 month as a course of treatment and 3 consecutive courses of treatment.The facial recovery after treatment was observed and its therapeutic effect was evaluated.Results The total effective rate and the score decrease index of freckles before and after treatment in the treatment group were 75.47%，（0.62±0.11），respectively，while in the control group，the total effective rate and the score decrease index before and after treatment were 56.52%，（0.45±0.24），respectively，the difference was statistically significant （P<0.05）.Conclusion The curative effect of Huoxue Mei granule combined with traditional Chinese medicine facial mask in the treatment of facial freckles is satisfactory.

Key words：Huoxuemei；Traditional Chinese medicine mask；Freckles

雀斑（freckles）是严重影响美容的一种常见的皮肤疾病，其病因与遗传倾向、常染色体显性遗传以及日晒或紫外线的照射密切相关，由于光照是引起皮疹发生的必需因素，临床上以光老化雀斑多见。传统的治疗方法常采用化學剂漂白或剥脱、液氮冷冻、机械磨削术、激光等， 虽有一定疗效， 但有的易遗留色素沉着、色素减退、瘢痕等不良反应[1]。而采用中药内服外用，调理内分泌平衡，纠正失调的内分泌系统，化瘀通络，改变体内色素淤积的状况，改善全身的循环，从源头上可控制雀斑的产生[2]。本文运用中药外敷内治的法则，使用自制活血美颗粒联合中药面膜对面部光老化雀斑病症的患者进行治疗，获得较好的疗效，现报道如下。

1资料与方法

1.1 一般资料 选自2016年9月～2018年8月西安市新城中医院确诊为光老化雀斑的年轻女性99例。……