APP下载

瑞芬太尼复合舒芬太尼在支撑喉镜手术中的运用

2018-12-26赵枝富刘琍

健康必读·下旬刊 2018年10期

赵枝富 刘琍

【摘 要】 目的 研究瑞芬太尼复合舒芬太尼在支撑喉镜手术中的运用。方法 支撑喉镜下声带息肉切除术的患者80例,随机分为2组(n=40):瑞芬太尼组(R组)、瑞芬太尼复合舒芬太尼组(RF组)。RF组以瑞芬太尼1.5 μg/kg+舒芬太尼0.2 μg/kg iv,R组瑞芬太尼2ug/kg iv,两组均以丙泊酚2.0 mg/kg iv意识消失后以琥珀胆碱1.5mg/Kg iv,肌颤后插管。麻醉维持:两组均以瑞芬太尼0.2 μg/(kg·min),丙泊酚6 mg/(kg·h)持续泵入,支撑喉镜置入前30秒分别静注琥珀胆碱0.5mg/kg。记录①两组各时段生命体征,②麻醉恢复情况,③0AAS评分。结果 (1)RF组比R组血流动力学更稳定,MAP、HR与基础值相比差异更小,术后咽痛及痛觉过敏发生率减少,有统计学意义(P<0.05),(2)两组自主呼吸恢复时间、睁眼时间、拔管时间、定向力恢复时间和离开恢复室时间及OAAS评分无统计学意义(P>0.05)。结论 瑞芬太尼复合舒芬太尼行支撑喉镜手术麻醉更平稳,可控性更好,是支撑喉镜手术麻醉的更好选择。

【关键词】瑞芬太尼;舒芬太尼;支撑喉镜

Application of remifentanil combined with sufentanil in laryngoscope surgery

Zhao Zhifu Liu li

The Peoples Hospital of Deyang City Sichuan Province 618000

abstract Summary Purpose To study the application of Rifentanyl combined with Shufentaini in the operation of supporting laryngoscope. Methods 80 patients with vocal polyp resection under laryngoscope were randomly divided into 2 groups(N = 40): Ruifentaini group(R group) and Shufentaini group(RF group). In the RF group, Ruifentaini 1.5 μg / kg + Shufentanyl 0.2 μg / kg IV and Rzuruifen 2 ug/kg IV, both groups lost their consciousness with propofol 2.0 mg/kg IV to amber choline 1.5 mg/kg Kgiv, Intubation after muscle fibrillation.Anesthesia maintenance: The two groups were continuously pumped with 0.2 μg /(kg · min) of rifentanyl, and propofol 6 mg /(kg · H), and amber choline was injected 0.5 mg/kg 30 seconds before the laryngoscopy was placed. Record the vital signs of each of the two groups, the recovery of anesthesia, and the score of 3 0AAS.Results(1) RF group was more stable in hemodynamics than R group, MAP and HR had less difference than base values, and the incidence of postoperative pharynx pain and pain allergy decreased, which was statistically significant(P<0.05),(2) There was no statistical significance in the two groups of autonomous respiration recovery time, opening time, pulling time, directional force recovery time and leaving recovery time and OAS score(P<0.05).Conclusion Refentanyl combined with Shufentainixing was a better choice for Suppressor laryngoscopy surgery.

Keywords Ruifentaini; Shufentaini; Support laryngoscope

【中圖分类号】R290 【文献标识码】A 【文章编号】1672-3783(2018)10-03--01

支撑喉镜下的声带手术对病人的有强烈的刺激,尤其是置入支撑架时,要求麻醉较深,尽量抑制各种神经反射,避免严重的心血管反应。由于大部分的支持喉镜手术时间短,较深的麻醉易导致病人术后苏醒时间延长,术后出现延迟呼吸抑制等并发症。瑞芬太尼是超短效的阿片类u受体激动剂,具有阵痛作用强,起效快,作用时间短,重复用药无蓄积,苏醒快等特点[1]。比较适合此类手术,但是瑞芬太尼使用量过大或时间长易致痛觉过敏[2]。舒芬太尼镇痛作用强,对呼吸、循环抑制轻,不影响患者意识。本研究比较瑞芬太尼联合舒芬太尼与单独使用瑞芬太尼在相同镇痛效价下是否更合适此类手术。……

登录APP查看全文