肌骨超声对类风湿性关节炎与痛风性关节炎骨质侵蚀的临床鉴别价值
2018-12-06姚黎丽徐华军韩运生李雄峰施林枫
姚黎丽 徐华军 韩运生 李雄峰 施林枫
[摘要] 目的 探讨肌骨超声对类风湿性关节炎与痛风性关节炎骨质侵蚀的临床鉴别价值。 方法 选取并收集35例类风湿性关节炎患者(A组)和35例痛风性跖趾关节炎患者(B组)的临床资料,回顾性分析患者关节的骨质侵蚀声像图特征,包括直接征象(骨侵蚀的边界、外形及血流信号)及间接征象(滑膜增生、痛风石、双轨征及点状高回声)。 结果 A组患者边界清晰率低于B组(χ2=36.7956,P<0.05),外形中的圆形率高于B组(χ2=19.8252,P<0.05),两组患者血流信号差异无统计学意义(χ2=1.4286,P>0.05);A组滑膜增生发生率高于B组(χ2=31.2306,P<0.05),痛风石、双轨征及点状高回声发生率均低于B组(χ2=32.0833,17.5000,19.0909,P均<0.05)。 结论 根据骨侵蚀的声像图特征,肌骨超声能够对类风湿性关节炎与痛风性跖趾关节炎进行鉴别。
[关键词] 类风湿性关节炎;痛风;跖趾关节炎;肌骨超声;骨侵蚀
[中图分类号] R445.1 [文献标识码] B [文章编号] 1673-9701(2018)30-0120-03
[Abstract] Objective To investigate the clinical identification value of musculoskeletal ultrasound in the diagnosis of rheumatoid arthritis and gouty arthritis. Methods The clinical data of 35 patients with rheumatoid arthritis(group A) and 35 patients with gouty arthritis of arthritis(group B) were selected and collected. The characteristics of bone erosion echography of the joints were analyzed retrospectively including direct signs (the edge of bone erosion, shape and blood flow signals) and indirect signs(synaptic hyperplasia, tophi, double-track and point-like hyperechoic). Results The edge clearing rate of patients in group A was lower than that in group B(χ2=36.7956, P<0.05). The circular rate in the shape was higher than that in group B (χ2=19.8252, P<0.05). There was no statistical difference in blood flow signals between the two groups(χ2=1.4286, P>0.05). The incidence of synovial hyperplasia in group A was higher than that in group B (χ2=31.2306, P<0.05). The incidence of tophi, double-track and point-like hyperechoic in group A were lower than those in group B(χ2=32.0833, 17.5000, 19.0909, all P<0.05). Conclusion According to the sonographic features of bone erosion, musculoskeletal ultrasound can identify rheumatoid arthritis and gouty arthritis.
[Key words] Rheumatoid arthritis; Gout; Metatarsal arthritis; Musculoskeletal ultrasound; Bone erosion
痛風性关节炎(gouty arthrisis,GA)和类风湿性关节炎(rheunatoid arthritis,RA)骨质侵蚀发生比较常见,容易引起关节畸形和功能丧失,早发现、早诊断、早治疗对延缓病程进展、保护关节功能和减少关节结构损伤具有重要意义[1]。在早发现、早诊断阶影像学技术发挥着重要作用,骨质侵蚀临床常用的诊断技术是X线,但对于早期患者鉴别诊断能力并不明显,缺乏一定的特异性和敏感性[2]。MRI虽然有较好的鉴别诊断效果,但由于费用较高难以在临床上广泛应用。随着医疗技术进步,肌骨超声得到了快速发展,在诊断骨质侵蚀方面具有较高的可靠性,但对于痛风性关节炎和类风湿性关节炎骨质侵蚀的鉴别诊断相关研究尚少[3],本研究选取我院收治的70例痛风性关节炎和类风湿性关节炎患者,探讨肌骨超声对类风湿性关节炎与痛风性关节炎骨质侵蚀的临床鉴别价值,现报道如下。……
