强肾固精方联合ACEI类药物治疗肾性高血压和肾性贫血的临床研究
2018-09-10董立明刘坤王静净刘立娜宋冰洁
董立明 刘坤 王静净 刘立娜 宋冰洁
摘要目的:验证强肾固精方联合ACEI类药物降低慢性肾炎患者的血压和提高血红蛋白含量总的临床效果。方法:选取2014年2月至2014年6月在唐山市中医医院住院及门诊的慢性肾小球肾炎患者160例,随机分为观察组(强肾固精方联合贝那普利组)和对照组(贝那普利组),每组80例。观察2组患者治疗前和治疗后血压和血红蛋白的数值,分析改善情况。结果:观察组在降低血压和提高血红蛋白的方面明显优于对照组,差异有统计学意义(P<005)。结论:强肾固精方联合ACEI类药物可明显降低血压和提高血红蛋白含量,对慢性肾炎有良好的疗效。
关键词肾小球肾炎;血压;血红蛋白;中西医结合;强肾固精方;ACEI类药物
Clinical Research on Strong Kidney Essence Combined ACEI Drugs in Treatment of Renal Hypertension and Renal Anemia
Dong Liming1,Liu Kun2,Wang JingJing2,Liu Lina2,Song Bingjie2
(1 Southern Chinese medicine hospital,Tangshan 633002,China; 2 Tangshan City Chinese medicine hospital,Tangshan 063300,China)
AbstractObjective:To test the strong kidney decoction combined with ACEI drugs to reduce blood pressure in patients with chronic nephritis and improve the clinical effect of total hemoglobin content.Methods:A total of 160 cases of chronic glomerulonephritis were randomly divided into the observation group (kidney gujingfang combined with Benner Pury group) and the control group (Benner Pury group),which were selected from Feb.to June,2014 in Tangshan City Chinese medicine hospital,with 80 cases in each group to observe the blood pressure and hemoglobin values.Two groups of patients before and after treatment,improvement was analyzed.Results:For the observation group,lowering blood pressure and improving hemoglobin was significantly better than the control group and the difference was statistically significant (P<005).Conclusion:Kidney decoction combined with ACEI drugs can significantly reduce blood pressure and improve the hemoglobin content and has good curative effect on chronic nephritis.
Key WordsGlomerular nephritis; Bblood pressure; Hemoglobin; Traditional Chinese and Western medicine; Strong kidney essence; ACEI drugs
中圖分类号:R2565文献标识码:Adoi:10.3969/j.issn.1673-7202.2018.07.020
慢性肾小球肾炎是临床常见病和多发病,其中肾性高血压和肾性贫血是慢性肾小球肾炎主要并发症之一,二者均是是导致肾功能衰竭主要原因[1]。很多患者未能有效缓解肾性高血压和肾性贫血,而使肾功能快速衰竭。所以关于这方面的研究显得尤为重要。目前二者的治疗方法有单纯西药治疗、纯中医及中西医结合治疗3种,单纯西药治疗只能改善一种症状,而不能同时改善高血压和贫血等症状。随着中医临床研究的深入发展,越来越多的学者关注中西医结合治疗的优越性,并且研究出治疗的新方法和新途径,已经得到了人们的认可,可同时改善患者高血压和贫血的临床症状,疗效显著。所以说深入开展中西医结合对慢性肾炎治疗作用及其机制的研究具有重要意义。所以本研究观察其对慢性肾小球肾炎患者的疗效和安全性。……
