尿液红细胞相位分析在肾病诊断中的应用
2018-09-03赵启波姜登强陈启斌
赵启波 姜登强 陈启斌
[摘要] 目的 探讨分析尿液红细胞相位分析在肾病诊断中的应用价值。方法 方便选取该院2016年1月—2017年1月收治的100例肾病患者,对其血尿结果的红细胞相位指标进行回顾性分析,主要包括尿红细胞形状分布,畸形红细胞率,尿红细胞色度分布以及尿红细胞宽度分布等,希望从以上分析中可以找出区分非肾小球性血尿和非肾小球性血尿的医学决定水平。结果 当畸形红细胞率大于70%,尿红细胞形状分布小于50%时,可以将肾小球性血尿以及临床符合率提升至95%;当畸形红细胞率小于30%,尿红细胞形状分布大于80%时,非肾小球性血尿与临床符合率能够达到95%。结论 在诊断肾病患者时,采用尿液红细胞相位分析诊断方式具有显著的诊断价值,值得在临床诊断上推广使用。
[关键词] 红细胞相位;尿液;肾病;诊断价值
[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742(2018)04(c)-0188-03
Application of Analysis of Urine Erythrocyte Phase in the Diagnosis of Nephropathy
ZHAO Qi-bo, JIANG Deng-qiang, CHEN Qi-bin
Department of Clinical Laboratory, Zhaotong First Peoples Hospital, Zhaotong, Yunnan Province, 657000 China
[Abstract] Objective To study and analyze the application value of analysis of urine erythrocyte phase in the diagnosis of nephropathy. Methods 100 cases of patients with nephropathy admitted and treated in our hospital from January 2016 to January 2017 were convenient selected, and the erythrocyte phase index of blood and urine results were reviewed, mainly including the distribution of urine red blood cell shapes, abnormal erythrocyte rate, distribution of erythrocyte chromaticity, RBC width distribution, and the medical determination level of glomerular hematuria and non-glomerular hematuria was analyzed. Results When the abnormal erythrocyte rate > 70% and urinary red blood cell shape < 50%, the coincidence rate of glomerular hematuria with the clinic increased to 95%, when the abnormal erythrocyte rate < 30% and the urinary red blood cell shape > 80%, the coincidence rate of non- urine erythrocyte phase with the clinic reached 95%. Conclusion The value of analysis of urine erythrocyte phase in the diagnosis of nephropathy is obvious, which is worth promotion and application in clinical diagnosis.
[Key words] Erythrocyte phase; Urine; Nephropathy; Diagnosis value
医学上包括的肾脏疾病类型主要有先天性多囊肾,膜性肾病,红斑狼疮肾病,过敏性紫癫肾病,慢性肾小球肾炎,肾盂肾炎以及隐匿性肾炎等[1]。肾脏疾病发展到后期可导致患者出现严重肾衰竭症状,还有可能对患者生命安全造成严重威胁。随着肾脏疾病的不断病变发展,患者在此期间会产生血尿情况。肾小球性血尿当中由于红细胞被过度挤压,出现了较多的异性红细胞。非肾性血尿患者的红细胞具有一致的形态和大小,主要是单一正常形态红细胞[2-4]。所以,需要通过全自动尿液沉淀分析仪器,统计分析尿液红细胞多参数检验结果,这样能够在较短时间内对血尿来源进行诊断和鉴别,可以加快处理患者的病情,降低其症状疼痛感。……
