短期胰岛素泵强化治疗对新诊断2型糖尿病患者胰岛素抵抗及胰岛B细胞功能的影响研究
2018-08-21李衍记
李衍记
[摘要] 目的 研究短期胰岛素泵强化治疗对新诊断2型糖尿病患者胰岛素抵抗及胰岛B细胞功能的影响。 方法 2017年6—11月选该院2型糖尿病112例患者分为两组。对照组用传统药物二甲双胍治疗。观察组使用短期胰岛素进行强化治疗。治疗后,对两组患者血糖稳定率及胰岛B细胞分泌释放水平对比。 结果 观察组的治疗方法患者的血糖稳定率高于对照组(χ2=9.67,P=0.015),观察组的治疗方法患者胰岛B细胞分泌释放水平高于对照组(χ2=10.48,P=0.027)。 结论 短期胰岛素泵强化治疗对新诊断2型糖尿病患者胰岛素抵抗及胰岛B细胞功能的影响显著。
[关键词] 胰岛素泵;2型糖尿病;胰岛素抵抗;胰岛B细胞
[中图分类号] R587 [文献标识码] A [文章编号] 1672-4062(2018)01(b)-0061-02
Research on Effect of Short-term Insulin Pumping Enhancement Treatment on the Insulin Resistance and Insulin B Cell Function of Patients Initially Diagnosed with Type 2 Diabetes
LI Yan-ji
Department of Endocrinology, Yankuang Group General Hospital, Zoucheng, Shandong Province, 273500 China
[Abstract] Objective To research the effect of short-term insulin pumping enhancement treatment on the insulin resistance and insulin B cell function of patients initially diagnosed with type 2 diabetes. Methods 112 cases of patients with type 2 diabetes in our hospital from November to June 2017 were selected and divided into two groups, the control group used the traditional drugs for treatment, while the observation group used the short-term insulin for enhancement therapy, after treatment, the stability rate of blood glucose and release level of insulin B cell secretion was compared between the two groups. Results The blood glucose stability rate in the observation group was higher than that in the control group(χ2=9.67, P=0.015), and the release level of insulin B cell secretion in the observation group was higher than that in the control group (χ2=10.48, P=0.027). Conclusion The effect of short-term insulin pumping enhancement treatment on the insulin resistance and insulin B cell function of patients initially diagnosed with type 2 diabetes is obvious.
[Key words] Insulin pump; Type 2 diabetes; Insulin resistance; Insulin B cell
糖尿病是人類众多疾病中的一种,近几年来,随着社会人群生活方式的改变以及工作和生活带来的种种压力使得糖尿病的患病率每一年都在大幅度的增长。中国2型糖尿病防治指南(2013年版)指出中国18岁以上人群糖尿病的患病率为9.7%,若同时以糖化血红蛋白(HbA1c≥6.5%)作为糖尿病诊断标准,则患病率为11.6%。我国医院对于糖尿病的认识也在逐年提升,在对糖尿病了解逐渐增多的情况下不断研究对糖尿病的最有效治疗方法。在新诊断的2型糖尿病患者中,常用二甲双胍等临床常规药物进行治疗[1]。2017年6—11月该次主要研究短期胰岛素泵强化治疗对新诊断2型糖尿病患者胰岛素抵抗及胰岛B细胞功能的影响,现报道如下。
1 资料与方法
1.1 一般资料
此次参与研究与治疗的是该院经临床医生新确诊为患有糖尿病2型的112例患者,观察组患者的年龄在56~83岁之间,平均年龄为(62.0±8.0)岁;……
