张军

[摘要] 目的 探讨莫西沙星治疗糖尿病合并下呼吸道感染的疗效。方法 收集该院2016年12月—2017年12月收治的糖尿病合并下呼吸道感染患者94例，随机分为两组各47例，观察组给予莫西沙星，对照组给予左氧氟沙星，比较疗效。结果 观察组总有效率为93.6%，明显优于对照组78.7%（P<0.05）；观察组FBG（6.3±0.5）mmol/L、2 hPBG（7.8±0.6）mmol/L，显著低于对照组（P<0.05）；两组不良反应比较差异无统计学意义（P>0.05）。结论 对糖尿病合并下呼吸道感染患者采用莫西沙星治疗，可有效提高治療效果，控制血糖，值得应用。

[关键词] 莫西沙星；糖尿病；下呼吸道感染；疗效

[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062（2018）03（a）-0093-02

[Abstract] Objective To study the curative effect of moxifloxacin in treatment of diabetes combined with lower respiratory tract infection. Methods 94 cases of patients with diabetes combined with lower respiratory tract infection admitted and treated in our hospital from December 2016 to December 2017 were collected and randomly divided into two groups with 47 cases in each， the observation group and the control group were respectively treated with moxifloxacin and levofloxacin， and the curative effect was compared between the two groups. Results The total effective rate in the observation group was obviously better than that in the control group （93.6% vs 78.7%）（P<0.05）， and the FBG （6.3±0.5）mmol/L，2 hPBG（7.8±0.6）mmol/L in the observation group were obviously lower than those in the control group（P<0.05）， and the differences in the adverse reactions between the two groups were not statistically significant（P>0.05）. Conclusion The moxifloxacin in treatment of diabetes combined with lower respiratory tract infection can effectively improve the treatment effect and control the blood glucose， and it is worth application.

[Key words] Moxifloxacin； Diabetes； Lower respiratory tract infection； Curative effect

糖尿病是临床常见的代谢性疾病。糖尿病患者由于长期高血糖引起代谢紊乱，可导致免疫系统功能低下，造成多系统感染或损害，其中呼吸系统是糖尿病合并感染的主要部位，约占45%[1]，也是糖尿病最常见的并发症之一，病死率可高达41%[2]。下呼吸道感染是呼吸系统常见的呼吸道疾病，其发生多见于支气管炎和支气管肺炎。两种疾病合并发生时常相互作用，相互恶化，不仅加重全身炎症反应，使呼吸道感染难以控制，还可发生酮症酸中毒或高渗性昏迷，对患者预后和生命造成严重影响[3]。制定正确的治疗策略，选择合适的抗菌药物，在减少病原菌耐药的同时减轻患者症状，提高治疗效果是治疗的关键。该文对该院2016年12月—2017年12月收治的94例糖尿病合并下呼吸道感染患者分组治疗，探讨两组治疗效果，报道如下。

1 资料与方法

1.1 一般资料

收集该院收治的糖尿病合并下呼吸道感染患者94例为观察对象，随机分为……