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难治性神经症MECT临床的应用与观察

2018-07-16李皖生何江丽房传龙

健康大视野 2018年5期

李皖生 何江丽 房传龙

【摘 要】目的:探讨无抽搐电休克(MECT)治疗难治性神经症的临床疗效及其作用“点”。方法:3年间收集我院确诊为难治性神经症的住院患者36例,随机分为研究组18例,接受药物联合MECT治疗;对照组18例,药物联合心理治疗。采用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA),脑地形图α、β波的功率值变化及治疗中出现的症状量表(TESS)评定疗效和不良反应。结果:接受 MECT治疗后的不同时间段病情获得了不同程度的改善,量表评分减少;脑电地形图额、中央区α波功率峰值增加。結论:MECT治疗对难治性神经症是一种最安全、有效的方法,值得一试。

【关键词】 无抽搐电休克;难治性神经症;脑地形图;安全有效

【中图分类号】R749.3

【文献标志码】A

【文章编号】1005-0019(2018)05-204-01

Abstract Objective:to investigate the clinical efficacy and function of non-convulsive electroconvulsive (MECT) in treating refractory neurosis.Methods: 36 patients admitted to the hospital with refractory neurosis were collected in 3 years, and 18 patients were randomly divided into the study group, and the drug was treated with MECT. Control grouP18 cases, drug combination therapy. Using Hamilton depression scale (HAMD), Hamilton anxiety scale (HAMA), brain topography changes of power value of alpha, beta, and treatment of symptoms scale (TESS) to evaluate the efficacy and adverse reactions. Results: after receiving MECT treatment, the conditions of the patients were improved with different degrees, and the scale score was reduced. The peak value of alpha wave power was increased in the frontal and central area. Conclusion: MECT is one of the most safe and effective methods to treat refractory neurosis.

Key words: non-convulsive electroconvulsive;refractory neurosis;brain topography;safe and effective

神经症是一组有一定人格基础,起病常受心理社会因素影响的精神障碍。主要表现为焦虑、抑郁、恐惧、强迫、疑病、躯体化症状,或神经衰弱症状。症状没有可证实的器质性病变基础,并与病人的现实处境不相称,但病人对存在的症状感到痛苦和无能为力,自知力完整或基本完整,病程多迁延。大部分患者经规范化的药物和心理治疗后,症状缓解,然而有少部分患者对治疗无反应,转变为“难治性神经症”。 难治性焦虑障碍:Durham RC等[1]认为“在充分治疗后、症状不缓解并且有加重趋势的焦虑障碍” ,难治性强迫症:患者经过足量(推荐剂量的最大剂量)足疗程(8-10周)包括氯米帕明的3种5-羟色氨再摄取抑制剂治疗无效[2]。难治性神经症往往共病多种综合征:焦虑、强迫、进食障碍、躯体变形障碍等等。……

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