探究彩色多普勒超声在新生儿缺氧缺血性脑病早期诊断中的应用价值
2018-06-20金燕子陈坛寿
金燕子 陈坛寿
[摘要] 目的 探討彩色多普勒超声在早期诊断新生儿缺氧缺血性脑病(HIE)中的应用价值。方法 方便选取2015年3月—2017年8月在该院出生并进行治疗的149例HIE患儿作为观察组研究对象,根据病情严重程度将其分为轻度组(47例)、中度组(63例)和重度组(39例),选择同期在该院出生的46名健康新生儿作为对照组。对所有新生儿出生后进行彩色多普勒超声动态监测,对检测结果进行比较。结果 对照组新生儿出生后24 h和48 h的Vs、Vd要明显高于观察组(P<0.05),且观察组中轻度组患儿明显高于中度组,中度组明显高于中度组(P<0.05);对照组新生儿出生后24 h和48h的RI则明显低于观察组,且轻度组明显低于中度组,中度组明显低于重度组(P<0.05)。CT诊断47例轻度HIE的诊断准确率为100.0%(47/47),MRI为93.6%(44/47),超声为74.5%(35/47),超声诊断轻度HIE的准确率明显低于CT和MRI(χ2=13.756,P=0.000; χ2=6.425,P=0.011),而在中重度HIE诊断准确率比较中,三者均差异无统计学意义(P>0.05)。结论 彩色多普勒超声可显示出HIE患儿出生后24 h脑血流的显著性改变,且操作方便、简单易行、可床旁操作、无创伤、经济性好,在HIE的早期诊断中具有较高的临床应用价值。
[关键词] 新生儿缺氧缺血性脑病;彩色多普勒超声;早期诊断
[中图分类号] R445.1;R722.1 [文献标识码] A [文章编号] 1674-0742(2018)02(c)-0186-03
The Application Value of Color Doppler Ultrasound in the Early Diagnosis of Neonatal Hypoxic-ischemic Encephalopathy
JIN Yan-zi,CHEN Tan-Shou
Ultrasound Department, Ningde Afflicted Hospital of Fujian Medical University, Ningde, Fujian Province,352000 China
[Abstract] Objective To investigate the application value of of Color Doppler ultrasound in the early diagnosis of neonatal Hypoxic-ischemic Encephalopathy (HIE). Methods 149 cases with HIE treated in our hospital from March 2015 to August 2017 were divided into the mild group (47 cases), the moderate group (63 cases) and the severe group (39 cases), and 46 healthy newborns were selected as the control group. The Color Doppler ultrasound testing results were compared among all newborns. Results After the birth of 24 hours and 48 hours, Vs, Vd and RI in the control group were higher than those in the observation group (P<0.05). The moderate group, the mild group and the severe group with Vs, Vd and RI also had significant differences (P<0.05). The diagnostic accuracy of CT diagnosis of 47 cases of mild HIE was 100% (47/47), MRI was 93.6% (44/47), ultrasound was 74.5% (35/47), the accuracy rate of ultrasound diagnosis of mild HIE were significantly lower than that of CT and MRI(χ2=13.756, χ2=6.425;P=0.000; P=0.011), and in severe accuracy HIE diagnosis rate comparison, there were no significant differences between the three(P>0.05). Conclusion Color Doppler ultrasound can show significantly HIE childrens 24h cerebral blood flow changes after the birth, and the operation is convenient, simple, can be operated bedside, with no trauma and good economy, it has high value in the early diagnosis of HIE.
[Key words] Neonatal Hypoxic-ischemic Encephalopathy; Color Doppler ultrasound; Early diagnosis
新生儿缺氧缺血性脑病(HIE)是造成新生儿脑损伤最为主要的原因,也是导致新生儿远期治理落后、脑性瘫痪、癫痫等发生的常见原因之一[1]。因此,早期诊断HIE对于尽早采取措施降低患儿的脑损伤,改善预后至关重要。一般对中度和重度HIE,由于患儿临床症状典型且明显,易于诊断,而轻度HIE则需通过CT、MRI、超声等影像学手段进一步检查确诊[2]。该研究方便选择2015年3月—2017年8月在该院出生病进行治疗的149例HIE患儿作为研究对象,对其进行CT、MRI和多普勒彩色超声检查,主要就彩色多普勒超声在HIE早期诊断中的应用价值进行探讨,以评价和明确其在HIE诊断中的效果,现报道如下。
1 资料与方……
