乌拉地尔对高血压合并急性心力衰竭患者心功能的影响
2018-06-13易青
易青
【摘要】 目的:探讨乌拉地尔对高血压合并急性心力衰竭患者心功能的影响。方法:选择笔者所在医院高血压合并急性心力衰竭患者200例,随机分成两组,每组100例。在常规治疗的基础上,对照组患者给予硝酸甘油,观察组患者予以乌拉地尔;记录并比较两组患者治疗前后心功能变化。结果:治疗7 d后,两组患者心功能指标均有所改善,且观察组LVEDD、LVEDV、LVEF及CI改善情况均优于对照组,差异均有统计学意义(P<0.05)。结论:乌拉地尔改善高血压合并急性心力衰竭患者心功能的效果优于硝酸甘油,值得临床推广。
【关键词】 乌拉地尔; 高血压; 急性心力衰竭; 心功能
doi:10.14033/j.cnki.cfmr.2018.7.014 文献标识码 B 文章编号 1674-6805(2018)07-0032-02
【Abstract】 Objective:To explore the effect of Urapidil on cardiac function in patients with hypertension complicated with acute mental exhaustion.Method:A total of 200 patients of hypertension complicated with acute heart failure in our hospital were selected and randomly divided into two groups,100 cases in each group.On the basis of conventional treatment,the control group was given Nitroglycerin,the patients in the observation group were treated with Urapidil;compared the changes of cardiac function before and after treatment between the two groups.Result:After the treatment of 7 days,the cardiac function indexes of the patients in two groups were improved,the LVEDD,LVEDV,LVEF and CI in observation group were better than those in the control group,the differences were statistically significant(P<0.05).Conclusion:Urapidil can improves the cardiac function of hypertensive patients with acute heart failure,which is better than Nitroglycerin,and is worthy of clinical promotion.
【Key words】 Urapidil; Hypertension; Acute heart failure; Cardiac function
First-authors address:Deyang Peoples Hospital,Deyang 618000,China
近年来,随着人们生活方式、饮食习惯的改变,心血管疾病的发病率逐年升高[1]。心力衰竭是由于心脏收缩功能和舒张功能出现障碍,无法将静脉回心血量充分地排出心脏,从而导致患者静脉系统血液淤积,而动脉系统血液灌流不足,最终引发心脏循环障碍症候群[2]。心力衰竭起病急,病情发展快,再加上患者常并发高血压、糖尿病及肾功能不全等多种疾病,心力衰竭发病原因复杂,增加了治疗难度,病死率与致残率较高,对患者的生命健康造成十分严重的消极影响[3]。血管扩张剂能够有效解除外周血管痉挛并改善患者急性恶化的血流动力学状况,缓解急性心力衰竭患者的临床症状,是急性心力衰竭治疗的主要药物[4]。本文讨论血管扩张剂乌拉地尔对高血压合并急性心力衰竭患者心功能的影响,现报道如下。
1 资料与方法
1.1 一般资料
选取2015年6月-2017年6月于笔者所在医院接受治疗的高血压合并急性心力衰竭患者200例,所选患者均符合《中国高血压防治指南2010》高血压的诊断标准[5];……
