王红丹　王淑荣

【摘 要】目的：研究超声引导下微波消融治疗子宫肌瘤的疗效及安全性。方法：选取2015年1月3日到2017年1月18日期间收治的26例子宫肌瘤患者作为研究对象，所选患者均采用超声引导下微波消融治疗，对其疗效及安全性进行分析。结果：对比治疗前后患者子宫肌瘤体积变化情况，患者经治疗后子宫肌瘤体积小于治疗前，差异显著（P<0.05）。所选患者经治疗后，53.85%治疗效果为显效，46.15%为有效，0.00%无效，总有效率为100.00%。治疗中患者偶感下腹胀痛，微波停止后无症状。治疗后2例患者出现不良反应，后均恢复正常。结论：超声引导下微波消融治疗子宫肌瘤具有显著疗效，且安全性较高，对患者治疗有积极作用，具有较高应用价值。

【关键词】超声引导；微波消融；子宫肌瘤；安全性

Abstract：Objective To study the efficacy and safety of ultrasound-guided microwave ablation for uterine fibroids. METHODS： Twenty-six patients with uterine fibroids who were admitted between January 3， 2015 and January 18， 2017 were enrolled. The selected patients were treated with ultrasound-guided microwave ablation， and their efficacy and safety were analyzed. RESULTS： Compared with the changes of uterine fibroid volume before and after treatment， the volume of uterine fibroids after treatment was less than that before treatment， and the difference was significant （P<0.05）. After treatment， 53.85% of the treatment results were markedly effective， 46.15% were effective， 0.00% was ineffective， and the total effective rate was 100.00%. During treatment， the patient felt a pain in the lower abdomen and was asymptomatic after the microwave was stopped. Two patients developed adverse reactions after treatment and returned to normal afterwards. Conclusion： Ultrasound-guided microwave ablation has significant curative effect on uterine fibroids， and it has high safety. It has a positive effect on the treatment of patients and has high application value.

【中圖分类号】R445.1 【文献标识码】A 【文章编号】1005-0019（2018）22--01

子宫肌瘤在育龄女性疾病中较为常见，临床表现多为月经过多、腹痛、贫血等。其在过去治疗中多应用子宫切除或肌瘤剔除术，而随着微创治疗的发展，射频技术得到广泛应用，且在应用中取得较好效果[1]。本文以收治的26例子宫肌瘤患者作为研究对象，所选患者均采用超声引导下微波消融治疗，对其疗效及安全性进行研究。

1 资料与方法

1.1 一般资料 选取2015年1月3日到2017年1月18日期间收治的26例子宫肌瘤患者作为研究对象，所选患者均经临床诊断及辅助超声检查确诊为子宫肌瘤[2]并开展超声引导下微波消融治疗。纳入标准：①已婚已育，希望保留子宫者；②肌壁间肌瘤或浆膜下肌瘤（不带蒂）者。排除标准：①月经、哺乳期患者；②凝血功能障碍严重者。所选患者中年龄在32-49岁，平均年龄（40.02±2.49）岁；浆膜下肌瘤7例，肌壁间肌瘤19例；肌瘤在4.0cm×4.5cm×5.1cm到7.9cm×6.4cm×6.2cm之间。所选患者均同意参加此次研究并由家属签署知情同意书。在医院伦理委员会同意并监督的情况下进行本实验。

1.2 方法 由经验丰富医师开展超声引导下微波消融操作，仪器应用微波消融治疗仪，微波频率为2450MHz，操作中由麻醉师监察患者体征，护理人员行仪器调控，静脉造影等。……