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地佐辛与芬太尼用于术后静脉镇痛的疗效比较

2018-01-25营大礼

中外医疗 2017年32期
关键词:效果

营大礼

[摘要] 目的 探析地佐辛与芬太尼用于术后静脉镇痛的临床效果。方法 方便选取该院2015年1月—2017年1月期间收治的108例行胸腹部及盆腔手术患者,根据术后镇痛方案不同将其随机分为观察组和对照组,各为54例,对照组采取芬太尼术后静脉镇痛,观察组采取地佐辛术后静脉镇痛,比较两组术后疼痛评分及不良反应发生情况等。结果 观察组术后1 h VAS评分(2.24±0.33)分、术后3 h(2.11±0.22)分、术后6 h(2.01±0.21)分、术后12 h(1.98±0.37)分、术后24 h(1.87±0.18)分、术后48 h(1.12±0.12)分与对照组比较差异有统计学意义(P<0.05);观察组不良反应发生率7.41%与对照组25.93%比较差异有统计学意义(P<0.05)。结论 地佐辛用于术后静脉镇痛临床效果确切,安全性好,值得临床进一步推广。

[关键词] 地佐辛;芬太尼;术后静脉镇痛;临床效果

[中图分类号] R587 [文献标识码] A [文章编号] 1674-0742(2017)11(b)-0105-03

[Abstract] Objective This paper tries to study the clinical effect of dezocine and fentanyl for postoperative intravenous analgesia. Methods From January 2015 to January 2017, 108 patients underwent thoracic abdominal and pelvic surgery were convenient selected and randomly divided into the observation group and the control group according to the different postoperative analgesia regimen, with 54 patients in each group. The control group was treated with fentanyl intravenous analgesia and the observation group adopted dezocine intravenous analgesia treatment, and the scores of postoperative pain and the occurrence of adverse reactions were compared between the two groups. Results The VAS score of 1h in the observation group was(2.24±0.33)points, the postoperative 3 h of(2.11±0.22)points, the postoperative 6 h of(2.01±0.21)points, the postoperative 12 h of (1.98±0.37)points, the postoperative 24 h of (1.87±0.18)points and the postoperative 48 h of (1.12±0.12) points, the difference was significant(P<0.05). The incidence of adverse reactions in the observation group was 7.41%, significantly lower than the control group of 25.93%, and the difference was significant(P<0.05). Conclusion Dezocine is effective in postoperative intravenous analgesia, with good clinical efficacy and high safety. It is worthy to be further popularized.

[Key words] Dezocine; Fentanyl; Postoperative intravenous analgesia; Clinical effect

通常情況下,手术后的患者均伴有不同程度上的疼痛,这也是临床上十分常见的急性疼痛,近年来,临床上对于术后疼痛的处理尚存在一定的不足,因此,随着研究的不断深入,越来越多的镇痛方法及新型麻醉药物不断被开发,广泛应用于临床实践中[1-2]。不过,目前依然没有一种方案或者药物能够获得完美的效果。术后自控镇痛时目前比较常见的镇痛方法,主要是通过中枢性神经作用起到镇痛的效果。地佐辛属于新一代的阿片类药物,芬太尼为常见的阿片类药物,在临床术中术后广泛使用[3-4]。为探析地佐辛与芬太尼用于行胸腹部及盆腔手术术后患者镇痛的效果,该文将2015年1月—2017年1月期间收治的108例行胸腹部及盆腔手术患者作为研究对象,现报道如下。

1 资料与方法

1.1 一般资料

方便选取该院收治的108例行胸腹部及盆腔手术患者……

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