崔鸿江++白璐璐++段秋霞++周瑾玮

[摘要]目的 分析某骨科医院近三年各临床科室活血化瘀类中药注射剂的使用现状，为促进临床合理用药提供参考。方法 回顾性调查2014年1月～2016年12月该院临床科室使用活血化瘀类中药注射剂的品种数、销售金额、用药频度（DDDS）、排序比等数据，综合评价该院的临床用药情况。结果 2014～2016年，该院各临床科室使用活血化瘀类中药注射剂的品种数和年销售金额均逐年递减；销售金额和用药频度排序靠前的品种主要集中在脑外科、创伤科和手显外科；不合理用药数从4345例下降到274例。结论 医疗机构应积极采用三级质控管理新模式，对临床不合理用药进行逐步规范。

[关键词]活血化瘀类；中药注射剂；不合理用药；分析

[中图分类号] R286 [文献标识码] A [文章编号] 1674-4721（2017）09（a）-0146-03

Analysis on irrational application of traditional Chinese medicine injection for promoting blood circulation and removing blood stasis in clinical departments of orthopedic hospital

CUI Hong-jiang BAI Lu-lu DUAN Qiu-xia ZHOU Jin-wei

Department of Pharmacy，the Second Affiliated Hospital of Inner Mongolia Medical University，Inner Mongolia Hohhot， 010010，China

[Abstract]Objective To analyze the status of traditional Chinese medicine injection of blood circulation and blood stasis in clinical department of orthopedic hospital for the past three years，and to provide reference for promoting clinical rational drug use.Methods Retrospective survey was conducted in the clinical department of the hospital from January 2014 to December 2016，and the clinical data of the hospital were evaluated comprehensively by the number of varieties，sales amount，frequency of drug use and sorting ratio.Results From 2014 to 2016，the number of varieties and annual sales of traditional Chinese medicine injection of blood circulation and blood stasis were decreased year by year.The ranking of sales and the frequency of medication mainly focused on brain surgery，trauma and hand significant surgical；unreasonable number of drugs decreased from 4345 cases to 274 cases.Conclusion The medical institutions should actively adopt the new model of three-level quality control management to carry out gradual standardization of clinical irrational drug use.

[Key words]Blood Circulation；Traditional Chinese medicine injection；Irrational drug；Analysis

活血化瘀類中药注射剂是一类具有活血、化瘀、通脉的特殊制剂，由于治疗心脑血管疾病疗效确切，已被临床广泛认可[1]。该类制剂还具有抑制凝血酶诱导的血小板中5-羟色胺的释放，抑制血小板的聚集，而具有抗凝血和改善血流动力学的特征，临床广泛用于术后静脉血栓的预防，改善微循环。近年来，该类制剂在骨科患者围术期预防深静脉血栓方面也被大量使用[2-3]，而在缺乏相关中医辨证施治理论基础的情况下，临床医生大量使用该类制剂也常导致各种超适应证、超剂量和超疗程等不合理用药情况的出现。本文对该骨科医院活血化瘀类中药注射剂的临床使用情况进行综合调查分析，以期促进该类制剂的合理使用。……