石磊++朱玲++李俊岑++王娜++魏家宾++高亮++康春雨

[摘要]目的：观察PDO（P-dioxanone）线与透明质酸联合治疗中下面部老化的临床效果。方法：收集2014年1月-2016年6月，行PDO线与透明质酸联合治疗中下面部老化的患者76例，采用双盲法，对就医者治疗前后按鼻唇沟形态标准、下颌缘形态标准进行评分比较，并观察其治疗效果。结果：术后随访3～24个月，失访3例，其余就医者面部老化均得到改善，对术后效果表示满意；就医者治疗后各项评分均低于治疗前，差异具有统计学意义，P<0.01。结论：PDO线联合透明质酸治疗中下面部老化的临床效果明显，尤其是治疗因面部容量丢失和面部皮肤松垂所致的面部老化更为显著，患者术后满意率高，值得推广。

[关键词]PDO；埋线提升；透明质酸；中下面部老化

[中图分类号]R622 [文献标志码]A [文章编号]1008-6455（2017）09-0011-04

Curative Effect Discussion of PDO Combined with Hyaluronic Acid in Mid-inferior Facial Aging

SHI Lei1，ZHU Ling2，LI Jun-cen2，WANG Na2，WEI Jia-bin2，GAO Liang2，KANG Chun-yu2

（1.Department of Plastic Surgery，Shihezi People's Hospital，Shihezi 832000，Xinjiang，China；2. Department of Plastic Surgery，Milanbavii Medical Aesthetic Hospital，Chengdu 610000，Sichuan，China）

Abstract： Objective To observe clinical curative effect of PDO（p-dioxanone）combined with the injection of hyaluronic acid in mid-inferior facial aging. Methods 76 patients who accepted the treatment of hyaluronic acid injection and PDO were followed up，and the treatment effect and prognosis were observed from January 2014 to June 2016. they were evaluated individually by nasolabial groove shape criterion and mandibular margin morphology standard at pre-and post-operation with double blind method. And the therapeutic effect was observed. Results All patients were followed up for 3 to 24 months， lost 3 patients. The facial aging of the rest of the patients improved， the satisfaction was satisfactory. The scores after treatment were lower than those before treatment， and the difference was statistically significant（P<0.01）. Conclusion PDO combined with hyaluronic acid is beneficial to improve the mid-inferior facial aging， especially in the treatment of facial aging due to loss of facial volume and facial skin laxity. Patients were highly satisfied with this treatment， and it is worthy of promotion.

Key words： PDO； thread lift； hyaluronic acid； mid-inferior facial aging

随着年龄的增加，会出现皮肤质量下降，皮下软组织容量缺失、松弛、移位等衰老征象，形成面部老化[1-3]。临床上有多种改善面部老化的方法，PDO埋线提升术因其创伤小、恢复快、效果明显等优点，而被越来越多的患者所接受。但相关研究表明[4]，PDO埋线提升对软组织容量缺失所致的面部老化改善不明显，致使一部分患者对术后效果欠满意。因此，为进一步提升面部老化治疗效果，本院采用PDO线与透明质酸联合治疗中下面部老化，术后患者满意度较高，现报道如下。

1 资料和方法

1.1 临床资料：2014年1月-2016年6月在米兰柏羽医学美容医院行PDO线联合透明质酸治疗的患者共76例，均为女性，年龄35～58岁，平均46岁。排除标准：①月经期，有血小板减少出血倾向者；②皮下脂肪过多或过少者；③面部赘皮过多者；④瘢痕疙瘩者；⑤面部有炎症，严重痤疮、感染、湿疹或牛皮癣者；⑥有心脑血管疾病、糖尿病等严重全身疾病者；……