张传英

摘要：1型糖尿病属于免疫性疾病的一种，主要是T淋巴细胞介导，患者的胰岛β细胞遭到攻击破坏而出现炎症，使得胰岛素的分泌不足从而发病，因此需要应用外源胰岛素进行治疗。要是患者的治疗不当或者是不够及时容易发生并发症甚至影响到他们的生命安全，给患者工作以及生活带来严重的不良影响，也加大了患者家庭的负担。研究人员认为该病的发生受遗传因素的影响，不过环境因素以及病毒感染诱发的患者数量也日益增多，因此发病机制较为复杂。当前情况下还缺乏彻底根治该病的方法，不过借助于严格控制血糖水平，避免并发症发生发展，能够有效延长患者寿命并提高他们的生活质量。

关键词：1型糖尿病；发病机制；表现；预防

中图分类号：R587.1 文献标识码：A 文章编号：1006-1959（2017）17-0027-03 To Prevent and Delay the Clinical Research Progress of Type 1 Diabetes Progression

ZHANG Chuan-ying

（Department of Endocrinology，Wuqing District Hospital of Traditional Chinese Medicine，Tianjin 301700，China）

Abstract：Type 1 diabetes is an immune disease，mainly T lymphocyte mediated，the patient's pancreatic β-cells were attacked and the destruction of inflammation，making the secretion of insulin and thus the incidence of disease，so the need for the application of exogenous insulin for treatment.If the patient's treatment is not enough or is not timely prone to complications and even affect their safety，to the patient's work and life has serious adverse effects，but also increased the burden on the patient's family.Researchers believe that the incidence of the disease affected by genetic factors，but environmental factors and the number of patients infected with viral infection is also increasing，so the pathogenesis is more complex.The current situation is also a lack of radical cure the disease，but with strict control of blood glucose levels，to avoid the development of complications，can effectively extend the life of patients and improve their quality of life.

Key words：Type 1 diabetes mellitus；Pathogenesis；Manifestation；Prevention

隨着人们生活质量的不断提高，再加上经济发展过程当中环境污染给人们带来的不良影响，糖尿病发展成为人类健康的重要威胁，根据该病发病原因的不同可以划分成两种类型，即1型以及2型糖尿病。1型糖尿病是因患者自身胰岛β细胞出现异常而产生的自身免疫喜用疾病。因胰岛β细胞异常导致胰岛素分泌不能满足自身生理功能为特点，发病机制多样化，不仅与遗传因素有关，外部环境及胰岛β细胞自身损伤关系密切。患者早期出现胰岛炎症过度至明显糖尿病症状时间较长，并且过程并无明显症状，糖尿病早期干预及治疗被患者忽视。……