胰岛素联合二甲双胍治疗2型糖尿病的疗效分析
2017-09-07于月霞
于月霞

[摘要] 目的 探讨分析胰岛素联合二甲双胍治疗2型糖尿病的疗效。方法 选取该院2016年1月—2017年1月收治的71例2型糖尿病患者统计分析,根据入院顺序进行编号并利用随机数表法分组(对照组,n=35;观察组,n=36),对照组患者采用二甲双胍治疗,观察组患者予以胰岛素联合二甲双胍治疗,观察对比两组患者的治疗效果。结果 观察组治疗后总有效率、低血糖发生率、临床相关指标以及各项血糖指标明显优于对照组(P<0.05)。结论 胰岛素联合二甲双胍治疗2型糖尿病的疗效显著,值得推广。
[关键词] 胰岛素;二甲双胍;2型糖尿病
[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062(2017)05(a)-0077-02
Clinical Analysis of Insulin Combined with Metformin in the Treatment of Type 2 Diabetes Mellitus
YU Yue-xia
Taixing City No.4 Peoples Hospital, Taixing, Jiangsu Province, 225400 China
[Abstract] Objective This paper tries to investigate the curative effect of insulin combined with metformin in the treatment of type 2 diabetes mellitus. Methods 71 cases of patients with type 2 diabetes in this hospital from January 2016 to January 2017 were selected and numbered according to the order of admission and grouped by random number table method. 35 cases were in the control group and 36 cases were in the observation group. The control group was treated by metformin and the observation group was treated by insulin combined with metformin, and the curative effects of both groups were observed and compared. Results The total curative efficacy, incidence of hypoglycemia, relevant clinical indexes and blood glucose index of the observation group after treatment was significantly better than that of the control group(P<0.05). Conclusion The curative effect of insulin combined with metformin in treatment of type 2 diabetes mellitus is remarkable, and it is worth promotion.
[Key words] Insulin; Metformin; Type 2 diabetes mellitus
2型糖尿病是一种成人型糖尿病,多发于35~40岁之后,其发生率约占糖尿病患者90%以上,近年来该疾病发生率在全球范围内呈现逐步增高趋势,特别是发展中国家增长速度更快,预计到2025年可能增至170%,成为当前严重威胁人类健康的重要疾病,因此加强治疗方案探讨具有重要的实践意义[1-2]。2016年1月—2017年1月該研究将71例2型糖尿病患者分别采用二甲双胍及其联合胰岛素的治疗效果进行对比研究,现报道如下。
1 资料与方法
1.1 一般资料
样本对象:采用随机抽样法从该院收治的病患中选取71例2型糖尿病患者展开研究。对照组男20例,女15例,平均年龄(56.2±4.3)岁。观察组男21例,女15例,平均年龄(56.6±4.5)岁。上述数据组间对比差异无统计学意义(P>0.05)。
1.2 方法
对照组患者采用二甲双胍治疗,推荐初始剂量为0.25 g/d,2次/d,于早晚进餐时服用,后期可根据患者血糖控制情况以及对药物的耐受性逐步增高剂量,1 d最大剂量≤2 g。观察组患者采用……
