宋益洲　高鹏　吴宪

[摘要] 目的 探讨急诊抢救重症哮喘结合小剂量肾上腺素治疗的效果。 方法 选取于2015年5月～2016年2月期间在我院接受治疗的52例重症哮喘患者，采用简单随机分组的方式将患者分为对照组与观察组，各26例。对照组给予常规急诊抢救，观察组则开展急诊抢救联合小剂量肾上腺素治疗，对两组患者的心率、呼吸频率、血氧饱和度变化情况进行比较，分析其发生不良事件的情况。 结果 治疗后，观察组患者的HR、呼吸频率以及血氧饱和度均明显较治疗前改善，且改善幅度明显大于对照组（P<0.05）；两组患者发生不良事件发生率比较，差异无统计学意义（P>0.05）。 结论 急诊抢救重症哮喘结合小剂量肾上腺素治疗的效果显著。

[关键词] 重症哮喘；急诊抢救；小剂量；肾上腺素

[中图分类号] R562.25 [文献标识码] A [文章编号] 1673-9701（2017）16-0010-03

[Abstract] Objective To investigate the effect of emergency treatment of severe asthma combined with low-dose adrenaline. Methods 52 patients with severe asthma treated in our hospital from May 2015 to February 2016 were chosen as the study subjects. The patients were divided into two groups by simple randomization grouping including control group and observation group，with 26 cases in each group. The patients in the control group were given routine emergency treatment， and the observation group was given emergency treatment combined with low-dose adrenaline treatment， The heart rate， respiratory rate， oxygen saturation changes between the two groups were compared to analyze the occurrence of adverse events. Results The heart rate， respiratory rate and oxygen saturation of the observation group after treatment were significantly improved compared with those before treatment， and the improvement was significantly greater than that of the control group（P<0.05）. The probability of adverse events in the two groups was not significantly different （P>0.05）. Conclusion Emergency treatment of severe asthma combined with low-dose adrenaline treatment effect is significant.

[Key words] Severe asthma； Emergency rescue； Low-dose； Adrenaline

哮喘在临床中属于较为常见的疾病，胸闷、气急、喘息以及咳嗽等均为该疾病较为常见的临床表现[1]，疾病严重可诱发患者出现心力或呼吸衰竭，对其生命安全存在极大的威胁[2]。伴随着肾上腺素用于重症哮喘抢救中效果的凸显，该药物在重症哮喘患者临床治疗中的应用效果亦成为目前临床研究的重点[3]。本次研究为探究对重症哮喘进行急诊抢救过程中使用小剂量肾上腺素的效果，特选取部分患者进行比较分析，现报道如下。

1 资料与方法

1.1 一般资料

选择2015年5月～2016年2月期间我院收治的重症哮喘患者52例纳入研究中，将其随机分为对照组与观察组，各26例。对照组中男12例，女14例，平均年龄（40.17±2.13）岁，平均病程（5.37±1.46）个月；观察组中男10例，女16例，平均年龄（40.73±2.08）岁，平均病程（5.43±1.06）个月。……