梁展婷+劳永霞

[摘要] 目的 分析欣母沛在治疗前置胎盘剖宫产产后出血的临床效果及安全性。 方法 选取在2015年6月～2017年2月期間在佛山市南海区桂城医院进行治疗的前置胎盘产妇100例，采用随机对照法将其分成观察组和对照组，各50例。对照组行子宫腔填塞纱条止血，观察组加用欣母沛止血。 结果 观察组和对照组的有效率分别为94.00%（47/50）及76.00%（38/50），差异具有统计学意义（P<0.05）；观察组产妇在产后2h和24h出血量较对照组明显减少，差异具有统计学意义（P<0.05）；观察组产妇的不良反应发生情况及行子宫切除情况显著好于对照组（P<0.05），观察组产妇在产前及产后2h的血氧饱和度、脉搏及血压等指标与对照组比较，差异无统计学意义（P>0.05）。 结论 欣母沛治疗前置胎盘产妇剖宫产的产后出血的临床效果较为明显，安全可靠，适合推广及应用。

[关键词] 欣母沛；前置胎盘；剖宫产；出血

[中图分类号] R714.461 [文献标识码] A [文章编号] 2095-0616（2017）08-85-04

[Abstract] Objective To analyze the clinical effect of hemabate in treatment of postpartum hemorrhage of cesarean section of placenta praevia and its security analysis. Methods 100 cases of maternal with placenta praevia cured in Foshan Nanhai District Guicheng Hospital from June 2015 to February 2017 were selected and divided into control group and observation group with 50 cases in each.Maternal in control group were treated with uterine packing gauze to stop bleeding，and maternal in observation group were treated with hemabate to stop bleeding. Results The effective rates of observation group and control group were 94.00% （47/50） and 76.00%（38/50），and the results were significantly different （P<0.05）.The blood loss of 2 h and 24 h in observation group was significantly lower than that in control group （P<0.05）.The adverse reaction and the incidence of adverse reactions of observation group were significantly better than those of control group （P<0.05）.There were no significant difference in blood oxygen saturation，pulse and blood pressure before and after 2 h between control group adn observation group（P>0.05）. Conclusion The clinical effect of hemabate in treatment of postpartum hemorrhage of cesarean section of placenta praevia is significant.It is safe and reliable.It is suitable for promotion and application.

[Key words] Hemabate；Placenta praevia；Cesarean section；Bleeding

前置胎盘为产妇常见的一种并发症，也是引起产后出血的原因之一。相关研究曾报道过，前置胎盘剖宫产后出血的发生率在3%～8%，由于患者子宫下端的肌肉组织偏薄，再进行剖宫产手术会因为子宫的收缩力较差，出现胎盘剥离困难，导致产妇产后出现凝血功能障碍及出血等危险[1]。临床上对前置胎盘剖宫产产后出现出血的主要治疗方法进行子宫按摩或者采用缩宫素等，若患者出现严重出血，需要结扎动脉甚至进行子宫切除。相关研究表明[2]，产后出血的治疗中最为有效的方法为使用宫缩药，近几年来，欣母沛作为宫缩药被广泛应用于产后止血的治疗中。本研究于2015年6月～2017年2月对我院诊治的前置胎盘剖腹产后出血产妇采用欣母沛和宫腔填纱进行止血，以探讨其临床治疗效果，现报道如下。

1 资料与方法

1.1 一般资料