管铮　陈玉红　邓振兴　蒋伯枫

[摘要] 目的 本文就復方丹参滴丸治疗冠心病心绞痛的临床效果进行分析探讨。 方法 选择我院自2015年3～12月期间收治的84例冠心病心绞痛患者作为研究对象，按入院就诊顺序随机编入观察组（42例）和对照组（42例），两组患者均给予消心痛口服治疗，在此基础上观察组再给予复方丹参滴丸治疗，比较分析两组冠心病心绞痛患者的临床治疗效果。 结果 观察组的临床治疗总有效率和心电图改善情况均明显优于对照组，差异具有显著性。与治疗前比较，对照组的高切全血粘度和低切全血粘度未明显改善，其余各项血液流变学指标均有明显降低，差异显著（P<0.05）。观察组患者治疗后血浆粘度、高切全血粘度、低切全血粘度和红细胞变形能力与治疗前相比均明显下降，差异有统计学意义（P<0.05），说明观察组能够改善血液流变学性状。结论 复方丹参滴丸治疗冠心病心绞痛效果显著，具有临床应用价值。

[关键字] 复方丹参滴丸；消心痛；冠心病心绞痛；临床分析

[中图分类号] R541.4 [文献标识码] B [文章编号] 1673-9701（2017）11-0097-03

Clinical analysis of compound Danshen dropping pill in treating angina pectoris of coronary heart disease

GUAN Zheng CHEN Yuhong DENG Zhenxing JIANG Bofeng

Department of Cardiology， the Northern Department of the Central Hospital of Yongzhou in Hunan Province，Yongzhou 425000，China

[Abstract] Objective To study the clinical effect of compound Danshen dropping pill in the treatment of angina pectoris of coronary heart disease. Methods 84 patients with angina pectoris CHD who were treated in our hospital from March to December 2015 were randomly divided into observation group（42 cases）and control group（42 cases） according to the order of admission. Patients of two groups were given oral treatment of isosorbide dinitrate. The observation group then was also given compound Danshen dripping pill treatment.The clinical treatment effect of patients with angina pectoris of coronary heart disease between the two groups was compared. Results The total effective rates of clinical treatment and electrocardiogram improvement in the observation group were significantly better than those in the control group. The differences were significant. The high shear blood viscosity and low cut whole blood viscosity did not significantly improve， the rest of the hemorheology indicators were significantly lower than before treatment in the control group，and the difference was statistically significant（P<0.05）. The plasma viscosity， high cut whole blood viscosity， low cut blood viscosity and erythrocyte deformability of the observation group were significantly lower than those before treatment，the differences were statistically significant（P<0.05）， indicating that the observation group can improve blood rheology traits. Conclusion Compound Danshen dropping pill is significantly effective in the treatment of angina pectoris of coronary heart disease and has clinical application value.

[Key words] Compound Danshen dripping pill；Isosorbide dinitrate；Angina Pectoris of coronary heart disease；Clinical analysis

冠状动脉粥样硬化性心脏病是冠状动脉硬化使管腔阻塞狭窄导致心肌缺血、缺氧而引起的心肌功能障碍和器质性病变，简称冠心病，也称缺血性心脏病[1]。根据《中国心血管疾病报告2013～2015》数据显示，2014年我国死于冠心病的患者高达1692万人，冠心病已成为威胁人类健康的重大疾病之一[2]。

目前，冠心病的治疗多采用药物维持治疗的方法[3]。常用的药物包括硝酸酯类、β-受体阻断药、钙通道阻滞剂、抗血小板、抗血栓形成药以及中药制剂。其中，西医通常是对症下药，不能从根本上解决问题，且治疗过程中不良反应较多，难以达到治疗效果[4]。为探索新的有效的冠心病治疗方法，选择本院2015年3～12月期间收治的84例冠心病心绞痛患者作为研究对象，分析复方丹参滴丸治疗冠心病心绞痛的临床效果，具体内容如下。……