赵学文+陈伯棠

[摘要]目的 探讨泛影葡胺加西甲硅油在术后早期炎性肠梗阻治疗中的作用。方法 回顾性分析我院2010年1月～2015年12月的45例术后早期炎性肠梗阻病例，将患者随机分为对照组（n=20）和治疗组（n=25）。对照组常规给予石蜡油治疗，治疗组给予泛影葡胺加西甲硅油治疗，比较两组的手术率、并发症发生率、术后首次排氣/排便时间、胃肠减压时间及住院时间。结果 两组保守治疗期间无明显并发症，均痊愈出院，无一例需手术治疗。治疗组的首次排气/排便时间、胃肠减压时间、住院时间显著短于对照组，差异有统计学意义（P<0.01）。结论 泛影葡胺加西甲硅油治疗术后早期炎性肠梗阻可加快肠道功能的恢复，缩短住院时间，值得临床推广应用。

[关键词]炎性肠梗阻；术后早期；泛影葡胺；西甲硅油

[中图分类号] R574.2 [文献标识码] A [文章编号] 1674-4721（2017）01（c）-0036-03

[Abstract]Objective To investigate the effect of Meglumine Diatrizoate plus Simethicone in the treatment of early postoperative inflammatory intestinal obstruction.Methods 45 patients with early postoperative inflammatory intestinal obstruction who were treated in our hospital from January 2010 to December 2015 were retrospectively analyzed and randomly divided into the control group （n=20） and the treatment group （n=25）.The control group was given routine Paraffin treatment，while the treatment group was treated with Meglumine Diatrizoate plusing Simethicone.The operation rate，complication rate，the postoperative first exhaust and defecation time，gastrointestinal decompression time and hospitalization time between the two groups were compared.Results There was no significant complications in the two groups during the conservative treatment.All cases were cured，there was no surgical treatment.The postoperative first exhaust and defecation time，gastrointestinal decompression time and hospitalization time in the treatment group was shorter than that in the control group，with significant difference （P<0.01）.Conclusion Meglumine Diatrizoate plus Simethicone in the treatment of early postoperative inflammatory intestinal obstruction may accelerate the recovery of intestinal function，shorten the time of hospitalization，it is worthy of clinical promotion and application.

[Key words]Inflammatory intestinal obstruction；Eearly period of postoperation；Meglumine Diatrizoate；Simethicone

术后早期炎性肠梗阻是指在腹部手术后早期（通常是在2周内）由于腹部手术创伤及腹腔内无菌性炎症等原因引起的肠壁水肿及渗出而形成的一种机械性与动力性同时存在的特殊类型的肠梗阻[1]，为腹部外科手术后常见的并发症之一。临床上多数患者经积极的非手术治疗，症状均可获得缓解，但治疗时间相对较长。近年来，笔者采用经胃肠减压管注入泛影葡胺加西甲硅油治疗术后早期炎性肠梗阻，取得了良好的效果，现报道如下。

1资料与方法

1.1一般资料

采用单盲法选取2010年1月～2015年12月本院收治的45例术后早期炎性肠梗阻患者作为研究对象，其中男28例，女17例；年龄21～75岁，平均（49.11±8.36）岁；既往均有腹部手术史。按照随机数表法将入选患者分为治疗组（25例）和对照组（20例）。……