张婉婷，高　芬



·临床报告·

两种角膜绷带镜在LASEK术后配戴的临床观察

张婉婷，高芬

Department of Ophthalmology, Kaifeng Central Hospital, Kaifeng 475000, Henan Province, China

•METHODS: Thirty-eight patients (76 eyes) who had undergone the LASEK were divided into two groups. One group of patients wore Balafilcon A, the other group of patients fitted with Senofilcon A. The lenses were worn continuously for 7d. This was a seven-day experience and the patients scored for the symptom of the eyes (sore eyes, foreign body sensation and tearing) on the third day and the seventh day. Both of the two groups of patients taken off the soft contact lens on the seventh day and let their vision and corneal staining checked.

•RESULTS: The symptoms of eye sore and tearing of the two groups patients were different. The patients who wore the Senofilcon A were better. The pain of eyes were also different at 3 and 7d after surgeries(Z=-4.146,P=0.000;Z=-2.814,P=0.005). The difference on tearing between the two groups at 3 and 7d after surgeries were significant (Z=-2.309,P=0.021;Z=-3.276,P=0.001). There was no difference on sensation of dryness between the two groups at 3 and 7d after surgeries (Z=-0.447,P=0.655; Z=-0.966,P=0.334). After the lenses were taken off, the visual acuity of patients wearing Senofilcon A was better (t=3.800,P=0.001); corneal staining showed limited spots in 1-2 quadrants with significant difference (Z=-2.384，P=0.017).

•CONCLUSION: The Senofilcon A (Johnson & Johnson Acuvue Oasys)and Balafilcon A (Bausch& Lomb pure vision) bandage contact lenses are safe and effective after LASEK, and the former is better than the latter in epithelial regeneration.

目的:评价两种角膜绷带镜Senofilcon A和Balafilcon A在准分子激光上皮下角膜磨镶术(laser-assisted subepithelial keratomileusis, LASEK)术后应用的临床安全性和有效性。

方法:行LASEK患者38例76眼，术后38眼配戴senofilcon A角膜绷带镜，38眼配戴Balafilcon A，连续配戴7d。术后第3、7d由患者对两眼主观症状(眼痛、异物感、流泪)进行评分。7d摘镜后检查视力和角膜染色情况。

结果:配戴两种镜片术后主观症状中眼痛感和流泪两眼存在差异，Senofilcon A眼症状更轻，眼痛感在术后3、7d两组比较差异有统计学意义(Z=-4.146，P=0.000；Z=-2.814，P=0.005)。流泪在术后3、7d时两组比较差异有统计学意义为(Z=-2.309，P=0.021；Z=-3.276，P=0.001)。而干涩感在术后3、7d时两组比较无统计学差异(Z=-0.447，P=0.655；Z=-0.966，P=0.334)。术后7d摘除镜片后，Senofilcon A眼视力优于Balafilcon A眼，差异有统计学意义(t=3.800，P=0.001)。两组摘镜后，角膜染色大多为1～2个象限的少量点染，对比有统计学差异(Z=-2.384，P=0.017)。

结论:Senofilcon A以及Balafilcon A角膜绷带镜在LASEK术后应用是安全有效的，Senofilcon A对角膜上皮瓣的恢复更优些。

角膜绷带镜；硅水凝胶；LASEK

引用：张婉婷，高芬.两种角膜绷带镜在LASEK术后配戴的临床观察.国际眼科杂志2016;16(7):1389-1391

0引言

准分子激光矫治屈光不正应用于临床已20多年，表层切削因简捷、安全、引入像差少[1-2]，而一直不能被基质切削取代，即使它有术后刺激症状较重、视力恢复稍慢，术后用药时间长等缺点。配戴合适的角膜绷带镜可以更好地减轻术后症状，促进创伤愈合。Senofilcon A(强生Acuvue Oasys)介绍可用于眼角膜手术患者作为绷带镜连续1wk配戴，Balafilcon A (博士伦pure vision)角膜绷带镜最长可连续配戴21d，本研究将两者一起做临床观察，现报告如下。

表1　术……