彭绮玲，杨秀章



·临床报告·

眼睑痉挛临床综合治疗的效果观察

彭绮玲，杨秀章

Department of Ophthalmology, the People’s Hospital of Baiyun District,Guangzhou 510500, Guangdong Province, China

•METHODS: Selected in our hospital, 60 cases (78 eyes) with blepharospasm were randomly divided into two groups, 30 cases 39 eyes in each group. The observation group were treated with compound anisodine injection combined with yi-qi-tong-luo acupuncture treatment, and supplemented by hot compress and massage, while the control group only with compound anisodine injection. We compared the treatment effect of the two groups.

•RESULTS: In the observation group, 38 eyes were clinically effective, 1 eye was invalid, 35 eyes marked, the total effective rate was 97%, the markedly effective rate was 90%; in control group, 32 eyes were the clinically effective, 7 eyes invalid, 23 eyes marked, the total effective rate was 82%, the markedly effective rate was 59%; the total effective rate and markedly effective rate of observation group were higher than those of the control group with statistical difference (P<0.05). The recurrence rates of the two groups were 5% and 34%, respectively, and the recurrence rate of the observation group was significantly lower than that of the control group (P<0.05).

•CONCLUSION: The compound anisodine injection combined with yi-qi-tong-luo acupuncture, hot compress and massage for blepharospasm, can significantly improve the efficiency of treatment, with higher effective rate and lower recurrence rate, compared with using compound anisodine alone.

目的：观察复方樟柳碱注射联合益气通络针刺、热敷及按摩综合治疗眼睑痉挛临床效果。

方法：选取我院眼科收治的眼睑痉挛病例60例78眼随机均分为两组，每组各30例39眼，治疗组采用复方樟柳碱注射联合益气通络针刺治疗，并辅以热敷及按摩，对照组仅采用复方樟柳碱注射治疗。比较两组治疗效果。

结果：治疗组临床有效 38眼，无效1眼，愈显35眼，总有效率分别为97%，愈显率90%；对照组临床有效32眼，无效7眼，愈显23眼，总有效率82%，愈显率59%；治疗组总有效率和愈显率较对照组高，差异有统计学意义(P<0.05)。两组治疗复发率分别为5%、34%，治疗组复发率显著低于对照组，差异有统计学意义(P<0.05)。

结论：采用复方樟柳碱注射联合益气通络针刺、热敷及按摩综合治疗眼睑痉挛，较复方樟柳碱单独治疗效果好，显著提高治疗有效率、愈显率，并降低复发率。

复方樟柳碱；益气通络针刺；热敷；按摩；眼睑痉挛

引用：彭绮玲，杨秀章.眼睑痉挛临床综合治疗的效果观察.国际眼科杂志2016;16(7):1383-1385

0引言

眼睑痉挛临床常表现为眼睑不自主性收缩，导致频繁性闭眼甚至功能性致盲，严重影响患者的日常生活、工作及学习等活动，属于面部局域性肌张力障碍疾病[1-3]。眼睑痉挛发病机制较复杂，主要包括精神、脑部血管异常、局部神经异常及遗传等多种因素，但其准确机制还尚无定论[4-5]。目前，临床治疗眼睑痉挛手段主要包括药物、手术、物理及中医，常用药物治疗包括口服卡马西平、氯硝安定、酰胺米嗪，或注射A型肉毒毒素、复方樟柳碱等[6-7]；……