侵入性及非侵入性操作对呼吸机相关性肺炎诊疗的意义
2016-10-21李志坚袁满涓霍保善张继平黄永光吴冠祺许建强李俭欢江丽嫦
李志坚,袁满涓,霍保善,张继平,黄永光,吴冠祺,许建强,李俭欢,江丽嫦
(广东省佛山市第二人民医院,广东 佛山 528000)
侵入性及非侵入性操作对呼吸机相关性肺炎诊疗的意义
李志坚,袁满涓,霍保善,张继平,黄永光,吴冠祺,许建强,李俭欢,江丽嫦
(广东省佛山市第二人民医院,广东 佛山 528000)
目的:探讨侵入性或非侵入性操作对呼吸机相关性肺炎(VAP)诊疗的意义。方法:收集2014年6月至2015年3月在我院重症医学科住院使用机械通气至少48 h以上,疑似VAP患者80例,随机分为非侵入操作组(F)、侵入操作组(Q)、混合组1(H1)、混合组2(H2),综合统计各组间VAP确诊率、ICU居住时间、抗生素使用时间、生存率、降钙素原水平、APACHEⅡ评分、氧合指数并进行分析。结果:侵入性操作较非侵入性操作能增加标本培养阳性率(P<0.05),但对VAP诊断率结果差异无统计学意义(P>0.05)。结论:非侵入性操作(如吸痰管气道内抽吸)可以达到侵入性操作相同诊断结果,同时具有低廉而又操作简便的特性。
侵入性操作;非侵入性操作;呼吸机相关性肺炎
[Abstract]Objective:To investigate the diagnosis and treatment significance of invasive and noninvasive operation for ventilator-associated pneumonia(VAP).Methods:A total of 80 cases of VAP suspected patients who had received mechanical ventilation at least 48 hours in ICU from Jun 2014 to Mar 2015 were enrolled.Patients were randomly divided into four groups including noninvasive operation group(F),invasive operation group(Q),mix group 1(H1)and mix group 2(H2).VAP diagnosis rate between groups as well as living time,antibiotic use time,survival rate,calcitonin levels and APACHE II score,oxygenation index were analyzed. Results:Specimen from invasive operation had higher specimens to cultivate positive rate than that from noninvasive operation(P<0.05),but there was no statistic significant difference in VAP diagnosis rate between two methods(P>0.05).Conclusion:Noninvasive operation collecting samples for VAP diagnosis is also accurate as invasive one.Collecting specimens from sputum suction tube in the clinical treatment on airway suction is a low cost and simple noninvasive operation.
[Key words]invasive operation;noninvasive operation;ventilator-associated pneumonia
随着机械通气技术的不断成熟,机械通气是重症监护室抢救危重患者的主要措施之一。呼吸机已成为现代ICU每个病床的床旁基本配置。呼吸机辅助呼吸治疗成功抢救了成千上万呼吸衰竭的患者。但随着呼吸机在ICU广泛应用及人工气道建立的增多,呼吸机相关性肺炎(ventilator-associated pneumonia,VAP)也成为各大ICU的重要病种。VAP的发病率一般在18%~60%,其病死率在30%~50%[1]。如何更有效地取得标本进行培养,明确致病菌,更早、更有针对性地使用有效抗生素治疗是治疗VAP成败的关键。……
