陈涛山东省泰安市中医医院肺病一科，山东泰安　271000

补肾化痰防喘方配合穴位贴敷治疗慢性阻塞性肺疾病的临床研究

陈涛
山东省泰安市中医医院肺病一科，山东泰安271000

目的 探讨补肾化痰防喘方配合穴位贴敷治疗慢性阻塞性肺疾病的临床效果。方法 将150例COPD患者随机分为试验组与对照组，各75例。对照组常规吸入布地奈德福莫特罗粉吸入剂（160∶4.5），1吸bid；试验组在对照组治疗的基础上加用补肾化痰防喘方同时配合穴位贴敷法治疗，10 d为1个疗程，连续治疗3个疗程。对比两组患者CAT评分、中医兼见症状评分及总疗效、1 s用力吸气容积占肺活量比例（FEV1%）、最大呼气流速（PEFR）、6 min步行距离及步行前后血氧饱和度下降分数、用药结束后慢阻肺复发例数及复发时间。结果 试验组在CAT评分、中医兼见症状评分及总疗效、1 s用力吸气容积占肺活量比例（FEV1%）、最大呼气流速（PEFR）、6 min步行距离及步行前后血氧饱和度下降分数、用药结束后慢阻肺复发例数及复发时间改善方面明显优于对照组（P<0.05）。结论 补肾化痰防喘方配合穴位贴敷可以改善患者肺功能，减少急性加重，改善患者症状、体征，提高生活质量，对慢性阻塞性肺疾病可起到积极的治疗作用。

补肾化痰防喘方；穴位贴敷；慢性阻塞性肺疾病；肾虚血瘀痰阻

[Abstract]Objective To explore the clinical effects of the formula of Bushen Huatan Fangchuan combined with point application therapy in the treatment of chronic obstructive pulmonary disease(COPD).Methods 150 COPD patients were randomly assigned to the experiment group and the control group,with 75 patients in each group.The control group was given regular inhalation of budesonide/fomoterol powder for inhalation(160∶4.5),with one inhaling bid.The experiment group was further given the formula of Bushen Huatan Fangchuan combined with point application therapy on the basis of the treatment in the control group.One course of treatment was 10 days,and 3 consecutive courses were taken for the treatment.CAT scores,scores of accompanied symptoms in TCM and overall curative effects,FEV1%, PEFR,6-minute walking distance and decreasing scores of oxygen saturation before and after walking,number of cases of relapsed COPD after drug administration and relapse time were compared between both groups.Results The improvement of CAT score,score of accompanied symptoms in TCM and overall curative effects,FEV1%,PEFR,6-minute walking distance and decreasing scores of oxygen saturation before and after walking,number of cases of relapsed COPD after drug administration and relapse time in experiment group were significantly higher than those in the control group(P<0.05).Conclusion The formula of Bushen Huatan Fangchuan combined with point application therapy is able to improve patients'pulmonary function,reduce acute aggravation,improve patients'symptoms and physical signs,and improve life quality,which shows active therapeutic effects on COPD.

[Key words]Formula of Bushen Huatan Fangchuan;Point application theropy;Chronic obstructive pulmonary disease; Kidney deficiency and blood stasis phlegm obstruction

慢性阻塞性肺疾病 （chronic obstructive pulmonary disease，COPD，简称“慢阻肺”）是以持续性气流受限为特征的可以预防和治疗的疾病，气流受限进行性发展，与气道和肺脏对有毒颗粒或气体的慢性炎性反应增强有关，急性加重和并发症影响着疾病的严重程度和对个体的预后[1]。本病的发病率较高，一旦发展为肺源性心脏病、呼吸衰竭，住院次数、花费极高，治疗效果不佳，预后极差，死亡率较高，是目前危害公众身心健康的主要病种之一。……